Two Pore Guys single-molecule diagnostic platform update

Two Pore Guys (2PG) has come a long way in a little over 18 months Background of Two Pore Guys At the recent Next Generation Diagnostics Conference in Washington DC (#NGDx18) Two Pore Guys had a nice exhibit where I had the privilege of meeting Tyler Shropshire Ph.D., their Sr. […]

Two Pore Guys Artist Rendition, kindly provided by 2PG

Google Artificial Intelligence for Pathology

Observations from American Association for Cancer Research 2018 #AACR18

It is something of a tradition for me to give some reviews of notable presentations from past AACR conferences. For example, here’s one that I did while at SeraCare for #AACR16, here’s one from #AACR15, and another one here from #AACR14. (Briefly looking for highlights from 2017, well it looks like […]


Learning content marketing and The Pillar Post

The world of content marketing is an ever-changing experience. A bit of history A few years ago it was a full-time effort to conduct video interviews, write blog posts, and help the sales team in other ways at Thermo Fisher Scientific’s Genetic Systems Division. (You can see some of that […]

The Pillar Post Pillar Biosciences

Bionano Genomics’ New DLS Saphyr Technology at #AGBT18

It has been almost five years since I wrote this post about Bionano Genomics and OpGen, and tools to look at structural variation. At that time OpGen was mapping bacterial genomes and Bionano Genomics would do insect genomes (about 100x as large), and the open question at that time was […]


Illumina’s iSeq 100 at #AGBT18 2

During the flurry of activity at the recent Advances in Genome Biology and Technology, I made it a point to take a close look at the newest CMOS-based NGS instrument from Illumina, called the iSeq 100. And it’s a good time to get a little perspective where next-generation sequencing has […]


NanoString’s Hyb & Seq Single Molecule Sequencer at #AGBT18

Background Back in 1989 in Belgrade Yugoslavia, Radoje Drmanac had an idea that would shape the next decade of genetic analysis, which was being able to sequence megabases of DNA information by a collection of 11-mers to 20-mers. Doing the mathematical calculations, this paper lays out what kind of DNA […]


NanoString’s Digital Spatial Profiling Microscope at #AGBT18

Now that another year has passed it is great to see the NanoString Digital Spatial profiling microscope near its commercial launch. The platform will be in early access to select customers in the fourth quarter of 2018, and full commercial launch in the first half of 2019. For those interested […]