Exponential technologies and electronic DNA detection

We are living in a world of exponential technologies, and genomics is one of several where expectations are not set at something 30% better or cheaper or faster, but 300% within the space of a few years. The term ‘exponential’ is starting to gain traction in the general public; here […]

Biological Dynamics – An Electronic cfDNA Detection Platform

While at the CHI Molecular Tri-Conference a few weeks ago, you can learn first-hand what you may have heard in passing but due to constraints of time had not had the chance to look into more deeply. Biological Dynamics is one such company; a colleague at SeraCare told me briefly […]

A handheld single-molecule diagnostic platform Two Pore Guys

One of the long-held goals for molecular testing of any sort (from testing the food supply for food-borne illness, to livestock health, to forensic testing, to testing for infectious disease, to screening for cancer) is to obtain inexpensive results without a lot of expensive equipment. The latest effort at ‘point-of-care’ […]

Bionano Genomics goes human-genome scale

A while back I wrote about a San Diego company setting out to produce optical maps of genomes called Bionano Genomics. It was November 2012 when I saw them exhibit for the first time at the American Society for Human Genetics, held that year in San Francisco, and decided to […]

NanoString’s Hyb & Seq single-molecule sequencing platform at AGBT 2017 2

Last year at Advances in Genome Technology and Biology, NanoString’s Joe Beechem presented their proof-of-concept work around a new single-molecule sequencing technology that had fulfilled a long-lived goal going back many years: sequencing by hybridization. (By the way, if you are interested here’s a 1994 paper by Lee Hood and Rade […]

Advances in genomic clinical applications

Genomic medicine will occur when research becomes translated into clinical and reduced to practice. Years ago Eric Green, the Director of the National Human Genome Research Institute (and one of the two organizers of the Advances in Genome Biology and Technology conference) would often talk about the need to make […]

Advances in Genome Technology

Many times the fun of AGBT is the advances in genome technology If you have attended Advances in Genome Biology and Technology in the past, sometimes there is amazing technology presented in a plenary session. Who can forget Stephen Turner’s electrifying talk in 2009’s meeting, complete with fireworks on the […]

The importance of data sharing 2

David Haussler (UC Santa Cruz): “Every clinician should be able to compare their genome to others.” Here at the first plenary session at the Advances in Genome Biology and Technology 2016, there is a mix of the strange and the familiar. Strange, in that we are not in Marco Island […]