Ion GeneStudio S5: The latest iteration of Thermo Fisher Scientific NGS 1

With the beginning of the influential JP Morgan Healthcare investor conference this week in San Francisco, you can expect an avalanche of news from companies large and small regarding all things therapuetic and diagnostic. With an official count of about 9,000 attendees, there are many more in San Francisco who […]


#AMP2017

Thoughts from the Association of Molecular Pathology conference #AMP2017

John Iafrede (Massachusetts General Hospital, MA) “There is a tidal wave of cell-free approaches; little performance testing; and the big question is who is going to pay for it.” This year’s Assocation for Molecular Pathology was held in Salt Lake City, Utah from November 15-18, 2017. (You can find the […]


Pillar Biosciences at Association for Molecular Pathology #AMP2017

While at the Association for Molecular Pathology in Salt Lake City Utah, I was able to interview Gang Song CEO of Pillar Biosciences to ask him about the challenges in the clinical laboratory that Pillar is tackling, about the basics of SLIMamp technology, and recent news. Check it out! #AMP2017


Association for Molecular Pathology annual meeting 2017 #AMP2017

Preview of Association for Molecular Pathology 2017 #AMP2017

With over 2000 clinical laboratory professionals in molecular diagnostics and pathology, plenty of technology and offerings on display. This year the Association for Molecular Pathology takes place in Salt Lake City Utah, and promises an abundance of new technology as well as the new accompanying science around diagnostic testing. Since […]


Formulatrix Constellation Digital PCR

Summary: A new digital PCR instrument with two different sample throughput formats (24 and 96), many more partitions, and more colors to enable multiplexing The digital PCR market continues growing, as it finds its continued utility for absolute quantitation of nucleic acids for a multitude of applications, from rare virus […]


A minor change to the Next Generation Technologist Blog

Five years and seven months ago (March 2012) the Next Generation Technologist blog had a set of four goals: An outlet to educate A place to build connections A forum to discuss A spot where the author can gain experience with web technology I can say that over this time […]


SlipChip technology for digital PCR

Executive “TL;DR” Summary: An interesting platform called SlipChip with potential point-of-care applications, for fast and potentially very inexpensive digital PCR Update: This work has been recently published (Oct 2017) in Science Translational Medicine. While at the recent Next Generation Diagnostics Summit (organized by the Cambridge Healthtech Institute and held in […]


Quanterix SR-Plex benchtop single-molecule digital detection technology

What will you do with 1000-fold improvement in sensitivity over standard immunoassays? What about 100-fold improvement in sensitivity over Luminex ones? The 1990’s were an exciting times in science. The Human Genome Project had published their first five-year plan (and thought then the human genome had 100,000 genes instead of […]