Monthly Archives: May 2012


Next-Generation Sequencing – its historical context

Even though the history of next-generation sequencing is short (the 454 GS20 came out in 2005, the Solexa 1G in 2007, and the SOLiD 2 in 2008), there is a robust genomic revolution going on, and a fierce battle in the marketplace with plummeting costs and soaring throughput. Whether Moore’s […]


How will the public learn about genomics and Next Generation Sequencing?

We’re on the verge of a new era in education. This week, the Smithsonian Museum announced a new genomics exhibit at the National History Museum, in conjunction with the National Human Genome Research Institute (NHGRI), and generous grants from several companies and institutions, including a major contribution from Life Technologies […]


The whole-exome vs. whole-genome sequencing debate

An enterprising salesperson from Complete Genomics used this newfangled social media thing called LinkedIn to make her mark on the world (perhaps) by posing a discussion question. (It was over at the ‘Genome Interpretation‘ group in case you were wondering.) Entitled, “The last days of exome sequencing“, she posed the […]


Some thoughts on Pacific Biosciences single-molecule sequencing

We’re living through a time this year of market transition. The Illumina HiSeq continues to have a strong market position (although the upcoming Ion Torrent Proton sets out to change that, however it won’t be available until this September / October). For the time being, customers with NGS platforms are […]