Cancer


A new role at a cell-free tumor DNA oncology testing company Sysmex-Inostics 1

With digital PCR OncoBEAM and NGS Plasma SafeSEQ technologies sensitive to 0.02% and 0.05% MAF respectively, expect to hear more from Sysmex-Inostics for biomarker development, companion diagnostic commercialization and patient testing It isn’t unusual for me to be found at different conferences, whether ASHG, AGBT, AACR or occasionally Molecular Tri-Con […]


Mission Bio's Tapestri system

Single-cell companies Mission Bio and Celsee Inc. at American Association for Cancer Research 2019 #AACR19 1

Mission Bio’s single-cell targeted DNA enrichment by multiplex PCR shows additional capabilities they are developing, and Celsee’s CTC enrichment also claims sc-RNA-Seq and sci-ATAC-seq potential In 2015 at the AACR conference in Philadelphia PA I noticed a poster that looked eerily familiar – the formation of water-in-oil droplets (“emulsions”) via […]


Miltenyi MACSima Imaging and Arima Genomics debut at the American Association for Cancer Research 2019 #AACR19

High-content imaging continues to be a theme, and will Hi-C become a popular research tool? Yesterday Akoya Biosciences showed a system that could do 50 fluorescent markers for high-content imaging of tissue samples, with a separate stage the mounts on an existing fluorescent microscope. Nanostring also celebrated the GeoMx launch […]


Detecting cancer four years before conventional diagnosis

Announcing a big move for Dale affecting his family, his employer, his colleagues, and his friends Note: This article originally appeared on LinkedIn. The magic wand of early detection Several years ago at a meeting with sales management, someone asked a provocative question: “If you had a magic wand, what […]


Observations from American Association for Cancer Research 2018 #AACR18

It is something of a tradition for me to give some reviews of notable presentations from past AACR conferences. For example, here’s one that I did while at SeraCare for #AACR16, here’s one from #AACR15, and another one here from #AACR14. (Briefly looking for highlights from 2017, well it looks like […]

Google Artificial Intelligence for Pathology

NanoString’s Digital Spatial Profiling Microscope at #AGBT18

Now that another year has passed it is great to see the NanoString Digital Spatial profiling microscope near its commercial launch. The platform will be in early access to select customers in the fourth quarter of 2018, and full commercial launch in the first half of 2019. For those interested […]


Ion GeneStudio S5: The latest iteration of Thermo Fisher Scientific NGS 1

With the beginning of the influential JP Morgan Healthcare investor conference this week in San Francisco, you can expect an avalanche of news from companies large and small regarding all things therapuetic and diagnostic. With an official count of about 9,000 attendees, there are many more in San Francisco who […]


Thoughts from the Association of Molecular Pathology conference #AMP2017

John Iafrede (Massachusetts General Hospital, MA) “There is a tidal wave of cell-free approaches; little performance testing; and the big question is who is going to pay for it.” This year’s Assocation for Molecular Pathology was held in Salt Lake City, Utah from November 15-18, 2017. (You can find the […]

#AMP2017