Single Molecule


Nabsys single molecule mapping technology

Another interesting single-molecule technology is a company out of Providence (RI) called Nabsys. For several years I had heard the name involved in developing single-molecule sequencing technology, and this technology will start its initial product around genomic mapping, rather than sequencing. For background on genomic mapping and CNV analysis along […]

Close-up of Nabsys Chip

Borrowed from a Oxford Nanopore Video (without permission)

Oxford Nanopore at AGBT 2014 2

A few attending the Advances in Genome Biology and Technology meeting in Marco Island Florida (February 12 – 15 2014) have blogged about a presentation from David Jaffe (Broad Institute), presenting the first data the next-generation sequencing community has publicly seen from Oxford Nanopore Technologies. For those not familiar with […]


Biopsy of skin sample courtesy of euthman via Flickr

Single molecule in-situ RNA startup Advanced Cell Diagnostics

FFPE (Formalin-fixed paraffin embedded) tissues are standard preparations in the clinical world. It has been estimated that there are millions of FFPE samples stored in countless hospital laboratories and research pathology groups, all part of a standard operating procedure among pathologists and other hospital personnel. These tissue samples are embedded […]


Photo of an OpGen mapping card

Single molecule mapping OpGen making slow progress 2

In contrast to BioNano Genomics, who is starting commercialization with early access customers now and full commercial launch in the Spring of 2013, OpGen launched the Argus™ Optical Mapping system in the summer of 2010. Their customers use this system for microbial strain mapping, mainly for infectious disease research or […]