January 28, 2013
by Dale Yuzuki
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FFPE (Formalin-fixed paraffin embedded) tissues are standard preparations in the clinical world. It has been estimated that there are millions of FFPE samples stored in countless hospital laboratories and research pathology groups, all part of a standard operating procedure among … Continue reading
January 25, 2013
by Dale Yuzuki
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A few weeks ago at the J.P. Morgan Healthcare Summit in San Francisco, Illumina announced that they acquired a startup company called Moleculo that provides virtual long reads of 8 to 10kb. Single molecule sequencing will provide long reads (Pacific … Continue reading
November 16, 2012
by Dale Yuzuki
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In contrast to BioNano Genomics, who is starting commercialization with early access customers now and full commercial launch in the Spring of 2013, OpGen launched the Argus™ Optical Mapping system in the summer of 2010. Their customers use this system … Continue reading
November 12, 2012
by Dale Yuzuki
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ASHG 2012 in San Francisco is finally over! The exhibit booths get torn down, the equipment gets packed up and shipped to storage, and hundreds of foot-weary front-line soldiers get back to their normal routines, whether in sales, marketing, product … Continue reading
November 9, 2012
by Dale Yuzuki
6 Comments
Here at ASHG 2012 in San Francisco this week, a ton of activity around the exhibitors, and Life Technologies does not disappoint with the Ion Bus on the show floor, an open 20 foot x 30 foot booth, a new … Continue reading
August 20, 2012
by Dale Yuzuki
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This past week I attended the Cambridge Healthtech Institute’s “Applying Next Generation Sequencing” meeting in Providence R.I. Attendance was down which is an indicator of the maturity of NGS technology, constrained travel budgets, or an oversupply of NGS conferences, and … Continue reading
July 25, 2012
by Dale Yuzuki
5 Comments
A few weeks ago this paper appeared in Nature Biotechnology, “Genome mapping on nanochannel arrays for structural variation analysis and sequence assembly”. It was the first publication of a startup company in San Diego called BioNano Genomics.
July 8, 2012
by Dale Yuzuki
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In previous posts I covered the basics of next-generation sequencing – library preparation, template preparation, and the sequencing methodology itself, whether by pyrophosphate detection, single base extension with reversible terminators, or probe addition by ligation. And single molecule sequencing’s attractiveness … Continue reading
July 2, 2012
by Dale Yuzuki
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Oxford Nanopore, based in Oxford U.K., made a remarkable announcement that surprised many in February’s AGBT meeting in Marco Island. A GridION and MiniION single-molecule sequencers were announced, promising 15 minute runtimes, no sample preparation, and a disposable USB-stick sequencer … Continue reading