next-generation sequencing


Centaur by {a href="http://www.flickr.com/photos/consciousvision/"}JustMN{/a} via Flickr.
The myth of the complete genome is something that is not commonly known to active observers of genomic technologies. (The term ‘active observer’ is from the point of view of one with varying degrees of background in the biological sciences, and is in noway an aspersion.) The ‘first draft’ of […]

Error, alignment, and the myth of the complete genome


Image from Oxford Nanopore
Oxford Nanopore, based in Oxford U.K., made a remarkable announcement that surprised many in February’s AGBT meeting in Marco Island. A GridION and MiniION single-molecule sequencers were announced, promising 15 minute runtimes, no sample preparation, and a disposable USB-stick sequencer for $900 (in the case of the MiniION), with 50kb […]

Oxford Nanopore, the first nanopore-based sequencing technology





Complete Genomics Logo 3
Complete Genomics is a startup business founded upon a particular idea – that the whole genome sequencing of human individuals is going to be industrialized, commonplace, and have such clinical utility so as to become the dominant application for next-generation sequencing. (Disclosure – I have no financial interest in this […]

Complete Genomics and the Whole Genome Sequencing market