Photo courtesy of {a href=""}kyz{/a} via Flickr Creative Commons. 2
A few days ago I reviewed in brief the history of Helicos Biosciences (HCLS), a company that held out the promise of single molecule sequencing, but failed to deliver on several fronts to the next-generation sequencing market. (This would include accuracy, throughput per dollar, and ease of use / reliability […]

What’s so special about single molecule sequencing?

Pacific BioSciences RS Sequencer, from their {a href=""}media kit{/a} page. 4
February 2008, Marco Island Florida – an exciting time in the world of NGS, the first pioneering papers were being published using short-read sequencing that are now every-day applications – ChIP, RNA-Seq, small RNA, the first whole genomes.  

Sequencing equipment provider Pacific Biosciences (PACB) and the rate of ...