General Business


Oxford Nanopore, the first nanopore-based sequencing technology

Oxford Nanopore, based in Oxford U.K., made a remarkable announcement that surprised many in February’s AGBT meeting in Marco Island. A GridION and MiniION single-molecule sequencers were announced, promising 15 minute runtimes, no sample preparation, and a disposable USB-stick sequencer for $900 (in the case of the MiniION), with 50kb […]


Helicos Single Molecule Sequencing – A Pioneer 8

The next-generation sequencing market continues its downward trajectory – routinely violating Moore’s Law by an estimated 3x, the cost per megabase curve started to significantly bend downward around 2007 when the Solexa 1G started selling in volume, and gave the 454 GS20 (as it was known then) the first competition […]


Next-Generation Sequencing – its historical context

Even though the history of next-generation sequencing is short (the 454 GS20 came out in 2005, the Solexa 1G in 2007, and the SOLiD 2 in 2008), there is a robust genomic revolution going on, and a fierce battle in the marketplace with plummeting costs and soaring throughput. Whether Moore’s […]


Career Advice and Executive Recruiters

I like hearing from recruiters, and can say that not only because they are salespeople and I am a salesperson at heart. They can be a critical source of difficult to find information, such as their ‘people network’ as well as which employer is looking for which type of talent. […]


A crazy time four times a year – the end of a quarter

This week is the last week of a financial quarter. Phones go unanswered, emails get put off, conference calls are rescheduled, and for many years (when I ‘carried a bag’), there would be a nervous pit in my stomach. So it goes in sales. There are tremendous benefits into going […]