A hopeful cure for SARS-CoV-2 with a combination of drugs

If the combination of hydroxychloroquine and azithromycin is confirmed by larger studies this actually could be “one of the biggest game-changers in the history of medicine” During this worldwide COVID-19 pandemic, now that states such as California and New York have enacted ‘stay at home’ orders, universities and many school […]

A new role at a cell-free tumor DNA oncology testing company Sysmex-Inostics 1

With digital PCR OncoBEAM and NGS Plasma SafeSEQ technologies sensitive to 0.02% and 0.05% MAF respectively, expect to hear more from Sysmex-Inostics for biomarker development, companion diagnostic commercialization and patient testing It isn’t unusual for me to be found at different conferences, whether ASHG, AGBT, AACR or occasionally Molecular Tri-Con […]

Cardea Bio graphene CRISPR-chip being loaded

Cardea combined with CRISPR enables amplification-free digital genomics

Cardea Bio Inc. and Nanosens Innovations Inc., Keck Graduate Institute and UC Berkeley detect two deleted DMD exons in 15 minutes down to 1.7 fM sensitivity We are currently living in an exciting time in molecular diagnostics, as the fields of chemical fluorescence, optics, electronics, microfluidics, biochemistry, genomics and nanofabrication […]

Dr. John Charles NASA at #AGBT19

Space travel to Mars at #AGBT19

An unusual presentation by a recently-retired NASA scientist Dr. John Charles shares an unusual and highly entertaining presentation entitled “From here to Mars: How the Twins Study and the year-long ISS mission have moved us closer to the red planet” The agenda of AGBT runs a wide range of topics, […]

The world’s first complete chromosome sequence at #AGBT19

NGHRI’s Dr. Adam Phillippy presents a remarkable dataset – the telomere-to-telomere assembly of a complete human X chromosome When the completion of the Human Genome Project was announced on June 6, 2002, President Bill Clinton said the following: We are here to celebrate the completion of the first survey of […]

The full x-chromosome map

The Long Read Club at #AGBT19

A Wellcome Trust supported effort, The Long Read Club seeks to resurrect a time-honored tradition: protocol development After a long 5 days away from home and work and the routines that surround it, attending AGBT (and likewise other major conferences) is a tremendous amount of work. I was teasing a […]

MGI Closes out #AGBT19 with a MGISEQ-T7 splash 1

According to one thought-leader, it was the highlight of Advances of Genome Biology and Technology 2019 in Marco Island FL Way back in 1997 Craig Venter and Daniel Cohen (co-founder of Millenium Pharmaceuticals, among other things) wrote an essay entitled ‘The Century of Biology’. Here we are a little under […]

The age of mRNA isoform discovery at #AGBT19

Single-cell isoforms from long-reads take the stage at the Advances for Genome Biology and Technology, along with structural variation and better reference genomes. Underlying all these advances is better long-read technology from Pacific Biosciences and Oxford Nanopore. Thinking a little further about the overarching theme of this year’s Advances in […]