MGI Closes out #AGBT19 with a MGISEQ-T7 splash 1

According to one thought-leader, it was the highlight of Advances of Genome Biology and Technology 2019 in Marco Island FL Way back in 1997 Craig Venter and Daniel Cohen (co-founder of Millenium Pharmaceuticals, among other things) wrote an essay entitled ‘The Century of Biology’. Here we are a little under […]


The age of mRNA isoform discovery at #AGBT19

Single-cell isoforms from long-reads take the stage at the Advances for Genome Biology and Technology, along with structural variation and better reference genomes. Underlying all these advances is better long-read technology from Pacific Biosciences and Oxford Nanopore. Thinking a little further about the overarching theme of this year’s Advances in […]


The early days of spatial genomics at #AGBT19

At #AGBT19 there is a palpable movement from dissociated single cells to single cells in situ Every year at the Advances of Genome Biology and Technology you can see what the future holds. When long-read sequencing was introduced in 2011, people here at AGBT19 are still talking about that Pacific […]

Illustration of Nanostring's GeoMx Digital Spatial Profiling technology

You can outsource just about anything

From specialty development, laboratory automation, and even IVD approval there options that abound Here at Advances in Genome Biology and Technology 2019 (#AGB19) you come across plenty of companies new and old. On one floor of the exhibitor suites I counted 17 companies, and on the second floor there were […]


Dolomite Bio – Drop-Seq for single-cell genomics

A commercial platform for droplet genomics Once upon a time Fluidigm had a single-system called the C1. Okay, it was back in September of 2013 that I wrote about it here; reading what I wrote way back then over five years ago there are newer and improved SMARTer cDNA kits […]

Dolomite Bio single-cell Nadia Instrument

SeqOnce RhinoSeq - a fast 40 minute workflow

SeqOnce’s RhinoSeq: 40 minute single-vial WGS or WES library preparation

There may still be room in NGS for innovation in workflow A few years ago Illumina’s Scientific Affairs team put together a gigantic wall-poster of all the different types of library preparation methods for next-generation sequencing (NGS). Today there are no less than three posters (one for DNA, one for […]


Nabsys 2.0 Single Molecule Mapping

Structural variation in genomics is a challenging task. To detect inversions, large deletions (by ‘large’ this is generally defined to be anything more than 50 bases or so), large insertions, and translocations in the genome takes a lot of creative alignment algorithms and hard work. Also you need to orthogonally […]

List of applications on the Nabsys 2.0 HD-Mapping Platform

#AGBT19 Advances in Genome Biology and Technology

#AGBT19 Advances in Genome Biology and Technology Preview

This year for the first time in three years the annual Advances in Genome Biology and Technology conference (#AGBT19) will be held back in Marco Island Florida, where it traditionally was held for many years. Those not familiar with AGBT, it is a specialty conference that began in the 1990’s […]


DNAfeed – AI-assisted Genetic Counseling on-demand

Pharmacogenetics, cancer genetics, cardiac genetics, WGS… AI-aided genetic counseling for healthcare organizations and genetic testing companies Artificial Intelligence (AI) is gaining in the popular consciousness. Last week, the White House announced The American AI Initiative with new investment, government AI R&D resources opened up, establishing AI governance and emphasizing education […]


Looking for new circulating biomarker signals with new technology

Here at the American Society for Human Genetics (#ASHG18) it has been several years since I’ve attended. The exhibit hall is as large as ever, plenty of new firms in DTC (Direct To Consumer) genomics, bioinformatics, and other technical feats are out in full-force. The new Singlera website is now […]


Detecting cancer four years before conventional diagnosis

Announcing a big move for Dale affecting his family, his employer, his colleagues, and his friends Note: This article originally appeared on LinkedIn. The magic wand of early detection Several years ago at a meeting with sales management, someone asked a provocative question: “If you had a magic wand, what […]


The Agile R100 handheld reader

The next leap in Personalized Medicine will be advances in sensor technology like Cardea

Can a graphene biosensor company like Cardea Biosciences play a role in making P4 medicine (predictive, preventive, personalized and participatory medicine) a reality? Lee Hood’s vision for P4 medicine It was about six years ago I attended a Personalized Healthcare conference at Virginia Commonwealth University in Richmond Virginia, where Leroy […]