Drukers: 'Sometimes the answer is right in front of you'. Shares George de Mestral's discovery of Velcro #AMP2015
9:46am November 5th 2015 via Hootsuite
Drukers:Historical context - RSV 1911, v-abl '70, oncogenes '76. Tyr kinases '79, bcr-abl '85 #AMP2015
Drukers: Shows paper from Nowell and Hungerford 1960, only 3 paragraphs. 'Breakthroughs often occur when different field converge' #AMP2015
9:45am November 5th 2015 via Hootsuite
Drukers: Shows more from this 1940 movie https://t.co/p8JCQ5eova #AMP2015
9:42am November 5th 2015 via Hootsuite
Drukers: CML is 5K new cases/y, 1-2 per 100K, 15% of all leukemias. Ave 50-60y age of onset. Median survival 3-5y in the 1970's #AMP2015
9:40am November 5th 2015 via Hootsuite
Drukers: Published in 1845, no typewriters, within six weeks of each other, 'Leucocythemia' and a debate for first publish date #AMP2015
9:39am November 5th 2015 via Hootsuite
Drukers: CML descr first 1834 (Bennet, Virchow), 1985 brc-abl, 2001 specific therapy for CML #AMP2015
9:38am November 5th 2015 via Hootsuite
Drukers: Mortality, 1900 vs 2000. Infections reduced w/sanitation, refrigeration (1920s), antibiotics (1942), vaccines (1955) #AMP2015
9:37am November 5th 2015 via Hootsuite
Drukers: Shows a B&W movie clip, Paul Ehrlich; 'I'm afraid marriage is out of the question' 'Does anybody ever get cured?' #AMP2015
9:35am November 5th 2015 via Hootsuite
Brian Druker (OHSU) "Anatomy of a breakthrough - Imatinib as a Paradigm of Targeted Cancer Therapies" #AMP2015
9:33am November 5th 2015 via Hootsuite
"Google has already replaced a lot of advice to give". Tsongalis: concludes a thought-provoking session! #AMP2015
9:00am November 5th 2015 via Hootsuite
Control, regulation, expertise. 'We think we are doing the right thing.' 'We need to embrace these things' #AMP2015
8:59am November 5th 2015 via Hootsuite
MDAnderson is using Watson - but still a need for a human to review the output and make a judgement. #AMP2015
8:58am November 5th 2015 via Hootsuite
Comment: For many this data is exciting to them - they have the time and interest to look deep into this. #AMP2015
8:53am November 5th 2015 via Hootsuite
Comment: Already happening, people discovering VUS, and broadcasting it, then finding others #AMP2015
8:51am November 5th 2015 via Hootsuite
Comment: Bad things will happen, and this market will be varied from someone who wants all info, others who want be told what to do #AMP2015
8:50am November 5th 2015 via Hootsuite
Discussion of cloud-based tool like Watson, with real-time journal searching, and community genetics, the new 'sharing' social gen #AMP2015
8:48am November 5th 2015 via Hootsuite
Audience: Remote telemedicine is a reality today for ICU's; perhaps a model for genetic counseling #AMP2015
8:45am November 5th 2015 via Hootsuite
Tsongalis: There will never be enough genetic counselors, to help all the people accessing this data. Possible: digital interaction #AMP2015
8:42am November 5th 2015 via Hootsuite
Audience: What about the medical professional? People will make poor choices w/data. Trained people need to interpret #AMP2015
8:41am November 5th 2015 via Hootsuite
Audience: Much lower amount of skill is needed, tech available. Tsongalis: MyGenome app from @illumina - indication of this #AMP2015
8:38am November 5th 2015 via Hootsuite
Audience: It would be good for society... Steve Lincoln: Already happening - people looking up ClinVar for themselves #AMP2015
8:36am November 5th 2015 via Hootsuite
Audience: You can't stop it, individ's will have an advantage by withholding from EMR 'and game the system' (interesting view) #AMP2015
8:31am November 5th 2015 via Hootsuite
From audience:DIY is fine, but what about when something comes up? Have 'we' done harm? We have access and others don't. #AMP2015
8:30am November 5th 2015 via Hootsuite
Tsongalis: Sequencing will become dirt-cheap; just for grins, it is going to happen. Will it be inside or outside regs? #AMP2015
8:28am November 5th 2015 via Hootsuite
Tsongalis: Q:Analogy to weight watchers? Yes, but - a regulated area. Regs and payors not keeping up. 23andme not as a company? #AMP2015
8:27am November 5th 2015 via Hootsuite
Tsongalis: The AMP organization may need to tackle this; or what other organization? All the different implications? (Discussion) #AMP2015
8:26am November 5th 2015 via Hootsuite
Tsongalis: A fine line - protection of information. Not an issue before - no means to test 'outside an official lab' #AMP2015
8:24am November 5th 2015 via Hootsuite
Tsongalis: Is this scenario recreational? Is this medical practice? Share genetic advice? Restrictions from employer? #AMP2015
8:23am November 5th 2015 via Hootsuite
Tsongalis: Closes with a scenario: friends start a 'genomics club'. They buy a used MiSeq, sequence their own genomes #AMP2015
8:20am November 5th 2015 via Hootsuite
Tsongalis: Quoting Weinstein from Dartmouth, 'you need to have a value-based strategy, not a volume-based one' #AMP2015
8:18am November 5th 2015 via Hootsuite
Tsongalis: Dartmouth working with Microsoft #Cortana digital assistant, similar to a fitbit band, w/9 sensors on it #AMP2015
8:17am November 5th 2015 via Hootsuite
Tsongalis: An iPhone turned into an EKG device, some req'd in hospital settings. Wearables in a shoe insole; 12M in the US now #AMP2015
8:16am November 5th 2015 via Hootsuite
Tsongalis:'We think we're pretty smart' but others are working on other things we don't know about. #AMP2015
8:13am November 5th 2015 via Hootsuite
Tsongalis: But other systems? Shows a @nanopore MinIon. Criticized for years; this year 200 papers on the system #AMP2015
Tsongalis: (Asked for a show of hands - pouring gels and counting bands.) But a photo of an @iontorrent PGM - but still in a lab #AMP2015
8:12am November 5th 2015 via Hootsuite
Tsongalis: What about decentralization - outside of the lab, at Walgreens - or a gas station? Shows a Sanger gel #AMP2015
8:11am November 5th 2015 via Hootsuite
Tsongalis: What if... everyone became well? If Theranos (or something like it) succeeds? DTC becomes routine? Home tests? #AMP2015
8:10am November 5th 2015 via Hootsuite
Tsongalis: The era of the Digital Human - @erictopol's books, Cook's book Cell (Amazon https://t.co/qRe0NmdJ4T ) #AMP2015
8:09am November 5th 2015 via Hootsuite
Tsongalis: Disruptive may not only be tech, but a new way of doing things, could be changing needs and expectations #AMP2015
8:08am November 5th 2015 via Hootsuite
Tsongalis: Note: If you want to see a @seracare interview of Greg about variability in FFPE / NGS see here https://t.co/FFAyS2S3eK #AMP2015
8:07am November 5th 2015 via Hootsuite
Forum #AMP2015 Greg Tsongalis (Dartmouth) Disruptive technologies and their effect on the traditional molecular diagnostics/molpath lab
8:05am November 5th 2015 via Hootsuite
Money-rich and time-poor - The Atlantic https://t.co/w9fUQE6Pie
7:40am November 5th 2015 via Hootsuite
Pointcare Genomics Awarded NCI Contract to Develop cfDNA Cancer Dx Tech | GenomeWeb Premium https://t.co/l1Exujhu26
6:10am November 5th 2015 via Hootsuite
Liquid Biopsy Assay May Predict Drug Resistance in Prostate Cancer Patients | GenomeWeb https://t.co/7PYDujaL28
4:40am November 5th 2015 via Hootsuite
RT @PatSchloss: I really wonder who is advising @illumina on 16S rRNA gene sequencing. About everything they do is wrong.
10:35pm November 4th 2015 via Hootsuite
MT @AppliedBio: LabCoat Live: Accelerate learning in a virtual environment that fits the lab’s busy schedule. https://t.co/dYyEOX1Tvt
9:31pm November 4th 2015 via Hootsuite
‘We are lucky to live on this era; before and after NGS; once technology hits, it’s here to stay’ panelist @QIAGEN #AMP2015
9:21pm November 4th 2015 via Hootsuite
“The saddest thing is to find out too late”; pt advocate @QIAGEN reception about a woman who is PD-1+ after a self-funded test #AMP2015
9:19pm November 4th 2015 via Hootsuite
Tad Lazarus @QIAGEN has analogy of focus on specs and HW in NGS at #AMP2015 to computers and punch cards, to today’s app focus and results
9:11pm November 4th 2015 via Hootsuite
