Lin: Can get good germline data from saliva, with their bacterial DNA informatics filtering. #NGDx15
8:51am August 18th 2015 via Hootsuite
Lin: Macro-dissection is important - removal of as much normal tissue as possible. ("Not micro-dissecting, yet") #NGDx15
8:49am August 18th 2015 via Hootsuite
Lin: Mark Raffeld, Liqiang Xi, Keith Killian acknowledged for their work here. (Good people I know at the NCI.) #NGDx15
8:48am August 18th 2015 via Hootsuite
Lin: Tissue: optimize extraction, path review, macro-dissect, track sample, integrate into IT and EMR systems, transport #NGDx15
Lin: They work closely with pathology for the right tissue. "Doesn't help if you sequence all you want and you had the wrong tissue' #NGDx15
8:46am August 18th 2015 via Hootsuite
Lin: PDXs are sequenced again (exome and panel, also RNA-seq). Workflow covers tissue proc, wet lab, IT, Bifx, clinical, protocol. #NGDx15
8:45am August 18th 2015 via Hootsuite
Lin: 2 db's - a research clinomics, another clinical EMR. Biopsies: Most is FFPE, used for both DNA, RNA; fresh tissue goes to PDX #NGDx15
8:44am August 18th 2015 via Hootsuite
Lin: Omics goes to research data, germline data, and somatic data. 2 separate tumor boards: one to sign out, another to decide care #NGDx15
8:42am August 18th 2015 via Hootsuite
Lin:Plasma for ctDNA, urine for add'l biomarkers. Workflow of patents are on two different protocols - 'Omics' and 'Precision Rx' #NGDx15
8:41am August 18th 2015 via Hootsuite
Lin: 'We use a lot of DNA, RNA' - and sure that in a few years much less will be needed; importance of biobanking of tissues, smpls #NGDx15
Lin: Also pt-derived tumor models (patient-derived xenografts, PDX), and biobanking, tissue repository of tumor, germline #NGDx15
8:40am August 18th 2015 via Hootsuite
Lin: Leaders at CCR (NCI), Paul Meltzer and Javed Khan for Clinical Omics program: clin platform; research (RNA and methylation) #NGDx15
8:39am August 18th 2015 via Hootsuite
Lin: Working at Hopkins with Vogelstein and Velculescu, worked on the first human exome (2006) http://t.co/4gv3by7DEp #NGDx15
8:38am August 18th 2015 via Hootsuite
Lin: Starts with a story about designing >10K primers and seeing many failures at Hopkins. Now WES for patients 'is routine' #NGDx15
8:35am August 18th 2015 via Hootsuite
Here at #NGDx15 Jimmy Lin (NCI) "NCI Clinomics Program: Clincal Cancer Panel and Exome Sequencing and Beyond"
8:33am August 18th 2015 via Hootsuite
RT @pknoepfler: Conversation with Harmit Malik on Gene Drive http://t.co/SdAzsn8bHr http://t.co/GGZKxsXlWJ
6:55am August 18th 2015 via Hootsuite in reply to pknoepfler
Transparency Weaponized Against Scientists http://t.co/8nfOjnDv6c
5:10am August 18th 2015 via Hootsuite
NIH to Award Up to $12M to Fund DNA, RNA Sequencing Research | GenomeWeb http://t.co/Mgm5az7vtm
4:40am August 18th 2015 via Hootsuite
RT @CarolineYLChen: Exclusive interview with 23andMe’s new CFO as startup prepares to relaunch health testing kit -- http://t.co/k99SS5j5l3
9:45pm August 17th 2015 via Hootsuite in reply to CarolineYLChen
Every county in America, ranked by natural beauty - The Washington Post http://t.co/XcCWPCLcl1
7:50pm August 17th 2015 via Hootsuite
RT @Helena_LB: These images of crystallized DNA by L. Gledhill are fantastic. #sciart http://t.co/o7caPKXqIr http://t.co/Wp7J5mxYus
6:20pm August 17th 2015 via Hootsuite
RT @aaronquinlan: Sequencing the unsequenceable: Expanded CGG-repeat alleles of the fragile X gene. (tx Evan Eichler) http://t.co/KcSUSoA20f
3:30pm August 17th 2015 via Hootsuite
Personal Genome: Rather Boring, Actually | GenomeWeb http://t.co/k3CeER7baA
2:20pm August 17th 2015 via Hootsuite
RT @GholsonLyon: Beacon Project Cracks the Door for Genomic Data Sharing - Bio-IT World http://t.co/5SPgeSuC4c
1:30pm August 17th 2015 via Hootsuite
RT @AppliedBio: Wouldn't this #ScienceHero Award looking smashing in your lab?http://t.co/KzMYIFcRc6 http://t.co/lPFd7AlgEr
12:30pm August 17th 2015 via Hootsuite
Also attending #NGDx15 http://t.co/Dp9Q2rGUkr RT @SeraCare: Meet the SeraCare #PrecisionMedicine team at #AACC2015! http://t.co/iPPJ6Nvmcv
11:25am August 17th 2015 via Hootsuite
If any of you are attending #NGDx15 in DC (starting tomorrow), be sure to pay me a visit @seracare ! Great lineup: http://t.co/Dp9Q2rGUkr
10:15am August 17th 2015 via Hootsuite
The Buffett Formula - reading is only part of the equation | Farnham Street http://t.co/hLWodd9afO
9:05am August 17th 2015 via Hootsuite
RT @ecancer: Cellular factors that shape the 3D landscape of the genome identified http://t.co/RdNT3pxFVn
8:50am August 17th 2015 via Hootsuite in reply to ecancer
RT @rahman_nazneen: Great new word - Metagrobology: the study of puzzles. I'm a practitioner. A couple to amuse/confuse you here! http://t…
6:49am August 17th 2015 via Hootsuite
RT @deannachurch: ICYMI: Come join my group @PersonalisInc http://t.co/u5teMiHucy #bioinformatics #jobs
6:25am August 17th 2015 via Hootsuite
RT @nytimes: Archaeologists think they've found clues to the fate of the "lost colonists" of Roanoke http://t.co/O2zZxQWiUU
5:25am August 17th 2015 via Hootsuite
Star Wars-Themed Lands Coming to Disney Parks | http://t.co/HnWL91xbLK http://t.co/ibEkx0YoMZ
4:40am August 17th 2015 via Hootsuite
RT @wef: Is online #education reaching the masses? http://t.co/HSvI1xky56 #MOOCs http://t.co/9RIe8vJi9j
10:15pm August 16th 2015 via Hootsuite
RT @NatGeoScience: Scientists can guess where users are going in life by the photos they upload: http://t.co/CNE2dJ8niv
9:15pm August 16th 2015 via Hootsuite
RT @gleonhard: “The phone is antithetical to deep reading,” said Maryanne Wolf, a neuroscientist at Tufts... http://t.co/NvS9iYZWJg
8:50pm August 16th 2015 via Hootsuite in reply to gleonhard
RT @mental_floss: Meet the Tritensil, a New and Improved Version of the Spork — http://t.co/TlQHtaUSMm http://t.co/CqyOz2DfUL
7:50pm August 16th 2015 via Hootsuite in reply to mental_floss
RT @wjsullivan: “Behold The Glorious, Glorious Official Poster For Star Wars: The Force Awakens” http://t.co/LByxvQBDMC
6:45pm August 16th 2015 via Hootsuite in reply to wjsullivan
RT @pickover: “Your MBA and PhD are impressive, but...” http://t.co/c4Jnk1BAc4
5:40pm August 16th 2015 via Hootsuite in reply to pickover
Misconceptions of Chance | Farnham Street http://t.co/zz7NEglJHA
4:05pm August 16th 2015 via Hootsuite
How To Learn How To Think | Farnham Street http://t.co/2qAhYGhwud
3:01pm August 16th 2015 via Hootsuite
Leisure, the Basis of Culture: Reclaiming Our Human Dignity in a Culture of Workaholism | Brain Pickings http://t.co/Me76w8HFSy
2:01pm August 16th 2015 via Hootsuite
How to succeed in business—er, remote IT work—without really trying | Ars Technica http://t.co/HxSFtdviWS
1:30pm August 16th 2015 via Hootsuite
This awesome Star Wars infographic shows off the series' influence on future franchises | TNW http://t.co/WQ1vJOw9rY
12:01pm August 16th 2015 via Hootsuite
Remember Spirograph? Then you need to play with this | TNW http://t.co/lcQYtYgDbP
11:01am August 16th 2015 via Hootsuite
MT @Helena_LB: Scientists have confirmed that nothing has any meaning | Wired http://t.co/3VYQlO00ZN
10:30am August 16th 2015 via Hootsuite in reply to Helena_LB
RT @rahman_nazneen: Google’s Alphabet is so ambitious they might as well have called it DNA http://t.co/ySz42TnIEl
9:35am August 16th 2015 via Hootsuite in reply to rahman_nazneen
RT @pickover: This is a paper analog computer from 1490. It is called a volvelle. http://t.co/Nz6Q9vuGTA http://t.co/2zSYpMZty8
8:25am August 16th 2015 via Hootsuite in reply to pickover
RT @TCGAupdates: The landscape of genes & infiltrating immune cells across human cancers http://t.co/SYRCqokZxN http://t.co/OAVlucuX6m
7:20am August 16th 2015 via Hootsuite in reply to TCGAupdates
Amazing #PMINetwork RT @mattmight: My @Quora answer to How can I minimize my chances of having a disabled child? http://t.co/ZmdRUwh100
6:10am August 16th 2015 via Hootsuite