Lin: Can get good germline data from saliva, with their bacterial DNA informatics filtering. #NGDx15

8:51am August 18th 2015 via Hootsuite

Lin: Macro-dissection is important - removal of as much normal tissue as possible. ("Not micro-dissecting, yet") #NGDx15

8:49am August 18th 2015 via Hootsuite

Lin: Mark Raffeld, Liqiang Xi, Keith Killian acknowledged for their work here. (Good people I know at the NCI.) #NGDx15

8:48am August 18th 2015 via Hootsuite

Lin: Tissue: optimize extraction, path review, macro-dissect, track sample, integrate into IT and EMR systems, transport #NGDx15

8:48am August 18th 2015 via Hootsuite

Lin: They work closely with pathology for the right tissue. "Doesn't help if you sequence all you want and you had the wrong tissue' #NGDx15

8:46am August 18th 2015 via Hootsuite

Lin: PDXs are sequenced again (exome and panel, also RNA-seq). Workflow covers tissue proc, wet lab, IT, Bifx, clinical, protocol. #NGDx15

8:45am August 18th 2015 via Hootsuite

Lin: 2 db's - a research clinomics, another clinical EMR. Biopsies: Most is FFPE, used for both DNA, RNA; fresh tissue goes to PDX #NGDx15

8:44am August 18th 2015 via Hootsuite

Lin: Omics goes to research data, germline data, and somatic data. 2 separate tumor boards: one to sign out, another to decide care #NGDx15

8:42am August 18th 2015 via Hootsuite

Lin:Plasma for ctDNA, urine for add'l biomarkers. Workflow of patents are on two different protocols - 'Omics' and 'Precision Rx' #NGDx15

8:41am August 18th 2015 via Hootsuite

Lin: 'We use a lot of DNA, RNA' - and sure that in a few years much less will be needed; importance of biobanking of tissues, smpls #NGDx15

8:41am August 18th 2015 via Hootsuite

Lin: Also pt-derived tumor models (patient-derived xenografts, PDX), and biobanking, tissue repository of tumor, germline #NGDx15

8:40am August 18th 2015 via Hootsuite

Lin: Leaders at CCR (NCI), Paul Meltzer and Javed Khan for Clinical Omics program: clin platform; research (RNA and methylation) #NGDx15

8:39am August 18th 2015 via Hootsuite

Lin: Working at Hopkins with Vogelstein and Velculescu, worked on the first human exome (2006) http://t.co/4gv3by7DEp #NGDx15

8:38am August 18th 2015 via Hootsuite

Lin: Starts with a story about designing >10K primers and seeing many failures at Hopkins. Now WES for patients 'is routine' #NGDx15

8:35am August 18th 2015 via Hootsuite

Here at #NGDx15 Jimmy Lin (NCI) "NCI Clinomics Program: Clincal Cancer Panel and Exome Sequencing and Beyond"

8:33am August 18th 2015 via Hootsuite

Transparency Weaponized Against Scientists http://t.co/8nfOjnDv6c

5:10am August 18th 2015 via Hootsuite

NIH to Award Up to $12M to Fund DNA, RNA Sequencing Research | GenomeWeb http://t.co/Mgm5az7vtm

4:40am August 18th 2015 via Hootsuite

RT @CarolineYLChen: Exclusive interview with 23andMe’s new CFO as startup prepares to relaunch health testing kit -- http://t.co/k99SS5j5l3

9:45pm August 17th 2015 via Hootsuite in reply to CarolineYLChen

Every county in America, ranked by natural beauty - The Washington Post http://t.co/XcCWPCLcl1

7:50pm August 17th 2015 via Hootsuite

RT @Helena_LB: These images of crystallized DNA by L. Gledhill are fantastic. #sciart http://t.co/o7caPKXqIr http://t.co/Wp7J5mxYus

6:20pm August 17th 2015 via Hootsuite

RT @aaronquinlan: Sequencing the unsequenceable: Expanded CGG-repeat alleles of the fragile X gene. (tx Evan Eichler) http://t.co/KcSUSoA20f

3:30pm August 17th 2015 via Hootsuite

Personal Genome: Rather Boring, Actually | GenomeWeb http://t.co/k3CeER7baA

2:20pm August 17th 2015 via Hootsuite

RT @GholsonLyon: Beacon Project Cracks the Door for Genomic Data Sharing - Bio-IT World http://t.co/5SPgeSuC4c

1:30pm August 17th 2015 via Hootsuite

If any of you are attending #NGDx15 in DC (starting tomorrow), be sure to pay me a visit @seracare ! Great lineup: http://t.co/Dp9Q2rGUkr

10:15am August 17th 2015 via Hootsuite

The Buffett Formula - reading is only part of the equation | Farnham Street http://t.co/hLWodd9afO

9:05am August 17th 2015 via Hootsuite

RT @ecancer: Cellular factors that shape the 3D landscape of the genome identified http://t.co/RdNT3pxFVn

8:50am August 17th 2015 via Hootsuite in reply to ecancer

RT @rahman_nazneen: Great new word - Metagrobology: the study of puzzles. I'm a practitioner. A couple to amuse/confuse you here! http://t…

6:49am August 17th 2015 via Hootsuite

RT @nytimes: Archaeologists think they've found clues to the fate of the "lost colonists" of Roanoke http://t.co/O2zZxQWiUU

5:25am August 17th 2015 via Hootsuite

Star Wars-Themed Lands Coming to Disney Parks | http://t.co/HnWL91xbLK http://t.co/ibEkx0YoMZ

4:40am August 17th 2015 via Hootsuite

RT @NatGeoScience: Scientists can guess where users are going in life by the photos they upload: http://t.co/CNE2dJ8niv

9:15pm August 16th 2015 via Hootsuite

RT @gleonhard: “The phone is antithetical to deep reading,” said Maryanne Wolf, a neuroscientist at Tufts... http://t.co/NvS9iYZWJg

8:50pm August 16th 2015 via Hootsuite in reply to gleonhard

RT @mental_floss: Meet the Tritensil, a New and Improved Version of the Spork — http://t.co/TlQHtaUSMm http://t.co/CqyOz2DfUL

7:50pm August 16th 2015 via Hootsuite in reply to mental_floss

RT @wjsullivan: “Behold The Glorious, Glorious Official Poster For Star Wars: The Force Awakens” http://t.co/LByxvQBDMC

6:45pm August 16th 2015 via Hootsuite in reply to wjsullivan

RT @pickover: “Your MBA and PhD are impressive, but...” http://t.co/c4Jnk1BAc4

5:40pm August 16th 2015 via Hootsuite in reply to pickover

Misconceptions of Chance | Farnham Street http://t.co/zz7NEglJHA

4:05pm August 16th 2015 via Hootsuite

How To Learn How To Think | Farnham Street http://t.co/2qAhYGhwud

3:01pm August 16th 2015 via Hootsuite

Leisure, the Basis of Culture: Reclaiming Our Human Dignity in a Culture of Workaholism | Brain Pickings http://t.co/Me76w8HFSy

2:01pm August 16th 2015 via Hootsuite

How to succeed in business—er, remote IT work—without really trying | Ars Technica http://t.co/HxSFtdviWS

1:30pm August 16th 2015 via Hootsuite

This awesome Star Wars infographic shows off the series' influence on future franchises | TNW http://t.co/WQ1vJOw9rY

12:01pm August 16th 2015 via Hootsuite

Remember Spirograph? Then you need to play with this | TNW http://t.co/lcQYtYgDbP

11:01am August 16th 2015 via Hootsuite

MT @Helena_LB: Scientists have confirmed that nothing has any meaning | Wired http://t.co/3VYQlO00ZN

10:30am August 16th 2015 via Hootsuite in reply to Helena_LB

RT @rahman_nazneen: Google’s Alphabet is so ambitious they might as well have called it DNA http://t.co/ySz42TnIEl

9:35am August 16th 2015 via Hootsuite in reply to rahman_nazneen

RT @pickover: This is a paper analog computer from 1490. It is called a volvelle. http://t.co/Nz6Q9vuGTA http://t.co/2zSYpMZty8

8:25am August 16th 2015 via Hootsuite in reply to pickover

RT @TCGAupdates: The landscape of genes & infiltrating immune cells across human cancers http://t.co/SYRCqokZxN http://t.co/OAVlucuX6m

7:20am August 16th 2015 via Hootsuite in reply to TCGAupdates

Amazing #PMINetwork RT @mattmight: My @Quora answer to How can I minimize my chances of having a disabled child? http://t.co/ZmdRUwh100

6:10am August 16th 2015 via Hootsuite