TI: TP53 frequency of 351 pt tumors - abt every instance. Illust. case of too consistent (unhelpful) / too random (unhelpful) #PAGXXIII
12:03pm January 12th 2015 via Hootsuite
TI: Of the ~100 somatic mut's, ~10 driver mut's. 2nd ref TP53: 2014 Nature Gen http://t.co/mmgo41IktW #PAGXXIII
12:02pm January 12th 2015 via Hootsuite
TI: Using cancer as an example, w/TCGA data 2013 Nature Methods http://t.co/HXhP02Plqh ~100 somatic exome mut's #PAGXXIII
12:00pm January 12th 2015 via Hootsuite
TI: Using a subway-map: how to do it computationally? Recent F1000 Cytoscape ref http://t.co/NmgOCWjkDs #PAGXXIII
11:58am January 12th 2015 via Hootsuite
TI: 2013 review of Genotype to Phenotype via Network Analysis Curr Opin http://t.co/1vMBJN6Wgs #PAGXXIII
11:57am January 12th 2015 via Hootsuite
TI: Better GWAS types of studies: methods to use networks to translate, and methods to assemble and visualize network models #PAGXXIII
11:56am January 12th 2015 via Hootsuite
TI: Genotype-Phenotype translations via Networks: what if insert a 'network knowledge base', combining other prior knowledge? #PAGXXIII
11:55am January 12th 2015 via Hootsuite
Trey Ideker (UCSD USA) "Interpreting genome variants and mutations using a unified human genetic network" #PAGXXIII
11:53am January 12th 2015 via Hootsuite
RT @KristinaLWeber: Swimming with polar bears - time to visit Canada http://t.co/ZGei7a5MQl #pagxxiii @bonesandbugs
11:46am January 12th 2015 via Hootsuite
RT @AdriSuarezGonz: NG documentary on polar bears http://t.co/lzOajMt5N6 @bonesandbugs #PAGXXIII
BS: Q:Max range of hybridization? A: The more genomes examined, the more hybridization seen. #PAGXXIII
11:42am January 12th 2015 via Hootsuite
BS: Photo of kids swimming in front of a polar bear: unseen glass plate (in Ottawa) 'don't do this at home' #PAGXXIII
11:40am January 12th 2015 via Hootsuite
BS: Repeated natural backcrossing from 12K years: isn't it an exciting time? What's next? (More samples to sequence...) #PAGXXIII
BS: HMM model with 'skip' states between Polar, het PB & Brown: emission prob's across the 3 states. Excess PP than expected #PAGXXIII
11:37am January 12th 2015 via Hootsuite
RT @DJ_de_Koning: Beth Shapiro: Swedish brown bear was 'PURE'; American bears all admixed! #PAGXXIII
11:34am January 12th 2015 via Hootsuite
BS: Ancient Irish bears are also admixture. Figure from 2011 Edwards Curr Biol http://t.co/4Wu98BYpVf #PAGXXIII
11:33am January 12th 2015 via Hootsuite
RT @pop_gen_JED: BS mtDNA says polar bears originated from brown. But nuclear says polar very diff from brown. Lots of admixture #PAGXXIII
11:30am January 12th 2015 via Hootsuite
BS: Miller 2012 PNAS Paper: http://t.co/zR6b1wwRnt #PAGXXIII
11:29am January 12th 2015 via Hootsuite
RT @taylorlawley: BS: Genome sequences added in Miller et al 2012 PNAS w/ the attached resulting phylogeny #PAGXXIII http://t.co/Z33yCxGyfJ
11:28am January 12th 2015 via Hootsuite
Beth Shapiro: "The evolutionary consequences of interspecies hybridization: insights from ancient and modern bear genomes" #PAGXXIII
11:27am January 12th 2015 via Hootsuite
RT @dgmacarthur: Great list. MT @joe_pickrell: Books and papers I’ve found useful while working in human genomics http://t.co/VmzANmeut7
10:55am January 12th 2015 via Hootsuite
RT @sebhtml: DNA Sequencing Could Map the Brain’s Wiring http://t.co/kgMguVRd3i @TechReview #biotechnology
9:55am January 12th 2015 via Hootsuite in reply to
RT @pickover: Set of stairs. Deep well of Chand Baori. http://t.co/ustiip7Hp0 http://t.co/s3f7QTZuIn
8:15am January 12th 2015 via Hootsuite
Does Retweeting Praise Make You a Monster? -- Vulture http://t.co/0oS34WcNBB
7:20am January 12th 2015 via Hootsuite
Where Will a Biology PhD Take You? Infographic|ASCB http://t.co/qHhoE78lau
6:30am January 12th 2015 via Hootsuite
RT @gedankenstuecke: This day I will now just cry a bit more: A Career in Science Will Cost You Your Firstborn http://t.co/ycXemmAETR
5:05am January 12th 2015 via Hootsuite
How to raise successful children — advice from parents lucky enough to know - The Washington Post http://t.co/ywFZi1QQzt
4:05am January 12th 2015 via Hootsuite
When personalized medicine, genomic research, and privacy collide. | Slate http://t.co/cwBIF9olDd HT @joyclee
3:20am January 12th 2015 via Hootsuite
PLOS Genetics: Modeling 3D Facial Shape from DNA http://t.co/FHL8luTzQn
2:20am January 12th 2015 via Hootsuite
RT @cbschicago: Did you read this story? Cold Snap Making Annual Lull In Blood Donations Worse http://t.co/p74r9ecyV4 http://t.co/YM4DtERqs2
1:50am January 12th 2015 via Hootsuite in reply to
RT @VentureBeat: Genetics testing company Invitae files for an initial public offering http://t.co/CpcJGoPx0Z
12:50am January 12th 2015 via Hootsuite in reply to
RT @joe_palazzolo: “The Snuggery now charges $50 for 45 minutes and $425 for an overnight cuddle session.” http://t.co/MkIde3ywyD
11:05pm January 11th 2015 via Hootsuite in reply to
Improve your conference experience with Twitter | Behind the Bench http://t.co/W5BZBN3mG9 #PAGXXIII
10:50pm January 11th 2015 via Hootsuite
PB: Goals of an open digital framework; short-term training opps; dev. discipline of biomedical data science and cross-training #PAGXXIII
10:04pm January 11th 2015 via Hootsuite
PB: Illus w/songbirds & human - Pfenning et al Science 2014 http://t.co/C2h6cXxXJM as an example of what could be done #PAGXXIII
10:03pm January 11th 2015 via Hootsuite
PB: What is the business model of a commons? A portion of a grant dedicated to IT: awarding credits instead #PAGXXIII
10:00pm January 11th 2015 via Hootsuite
PB: Describes a digital commons - a UID with metadata that is platform agnostic (public cloud, HPC, other platforms) #PAGXXIII
9:58pm January 11th 2015 via Hootsuite
PB: NIH's policy on data sharing: http://t.co/rnc9IJEuyM Also data citation: legitimize data as a form of scholarship #PAGXXIII
9:53pm January 11th 2015 via Hootsuite
PB: Community, Policy & Infrastructure: three elements of the Digital Enterprise. Intersection: sustainability, collab, training #PAGXXI
9:50pm January 11th 2015 via Hootsuite
PB: These problems are shared - BD2K Initiative website: http://t.co/omQuHnBbs6 What's the most efficient way to make data avail? #PAGXXIII
9:49pm January 11th 2015 via Hootsuite
PB: Nor do we have how all the data we have are used. No leverage of an Amazon or Netflix model "you may be interested in..." #PAGXXIII
9:46pm January 11th 2015 via Hootsuite
PB: But - no data sustainability plan in place yet. 'We don't have a 'how' for it' #PAGXXIII
9:44pm January 11th 2015 via Hootsuite
PB: Global communities are emerging - points out Global Alliance for Genomics & Health http://t.co/pSlspNV26L #PAGXXIII
PB: ADDS mission: an open ecosystem to enable research to be conducted 'as a digital enterprise'. http://t.co/xycuyGLklP #PAGXXIII
9:42pm January 11th 2015 via Hootsuite
PB: References 2012 Begley Nature on reproducing studies http://t.co/x0d6v29My6 and how it can affect funding #PAGXXIII
9:40pm January 11th 2015 via Hootsuite
PB: Illus how sol'ns can come from unexpected places - like working with gamers on crowdsourcing. But unintended consequences #PAGXXIII
9:38pm January 11th 2015 via Hootsuite
PB: Evidence is Waze, 3D printers. 'The Story of Meredith' Single-author paper. Unusual 15 y.o. Fora: http://t.co/8q01S1jg5n #PAGXXIII
9:37pm January 11th 2015 via Hootsuite
PB:Showed single CD from 1993 containing NCBI. Today: 40 Petabytes. 'Second machine age' AMZN - http://t.co/jnsLQGSIom #PAGXXIII
9:31pm January 11th 2015 via Hootsuite
PB: From an observational to a more analytical science: driven by inc amts of digital data. "Sociological more than anything" #PAGXXIII
9:30pm January 11th 2015 via Hootsuite
PB: "We're just at the beginning" in this #bigdata era. Finding, Accessing, Integrating, Reusing: 'digital research objects' #PAGXXIII
9:28pm January 11th 2015 via Hootsuite
