BW: TrophoGen now looking at Cysteine-Knot Growth-factor Superfamily. VEGF, PDGF... many product ideas #ResearchFest
2:20pm September 22nd 2014 via Hootsuite
BW: Second-generation: now applied to unmet needs in food supply / safety. W.Mariusz Szkudlinski, licensed tech from NIH #ResearchFest
2:18pm September 22nd 2014 via Hootsuite
BW: In 1998, FDA approval. hTSH (Thyrogen) becomes a top licensing income producer for the NIH. #ResearchFest
2:17pm September 22nd 2014 via Hootsuite
BW: 1986, a Technology Transfer Act passed; thyroid treatment idea; first with Integrated Genetics, SBIR, Genzyme, PIII trial #ResearchFest
2:14pm September 22nd 2014 via Hootsuite
BW: Interest going back many years is glycloprotein hormones. Human TSH genes; sugars were very impt. #ResearchFest
2:09pm September 22nd 2014 via Hootsuite
BW: ''The main quality all entrepreneurs have in common is OPTIMISM" "..to the point of hubris..." #ResearchFest
2:06pm September 22nd 2014 via Hootsuite
Session: "Commercial development of my research discoveries". First: Bruce Weintraub, of NIDDK, then TrophoGen #ResearchFest
2:05pm September 22nd 2014 via Hootsuite
Statement on Prize for Diagnostic Devices to Identify Antimicrobial Resistant Bacterial Infections - The NIH Director http://t.co/xEiaNAmK3D
1:00pm September 22nd 2014 via Hootsuite
MH: Best therapy now is Bt injection #ResearchFest
11:41am September 22nd 2014 via Hootsuite
MH: Writer's cramp: fingers abnormally flex or extend. Repetitive activity can lead to abnormal function #ResearchFest
MH: Can be eyelid control: frequent blinking video, blepherospasm. Neck control, hand control (piano playing, 1 pinkie) #ResearchFest
11:19am September 22nd 2014 via Hootsuite
MH: Dystonia prevalent about 16.5/100K. Sustained or intermittent muscle contractions. Video of child w/difficulty walking #ResearchFest
11:18am September 22nd 2014 via Hootsuite
Mark Hallett, NINDS “Focal hand dystonia: a failure of just one highly skilled movement” #ResearchFest
11:15am September 22nd 2014 via Hootsuite
AB: Optogenetic stimulation of the prefrontal cortex, in order to decrease cocaine-seeking behavior ResearchFest
11:01am September 22nd 2014 via Hootsuite
AB: Can use it to map pathways, create new therapeutics. Cocaine: low frontal cortex activity (outcome of decisions) #ResearchFest
10:57am September 22nd 2014 via Hootsuite
AB: Optogenetics: a revolution <10y ago, selecting a group of brain cells, injecting light-sensitive protein to visuallize #ResearchFest
10:54am September 22nd 2014 via Hootsuite
AB: Testing Pavlovian in Thorase KO mice: appetitive learning is impaired; ongoing research with cocaine & synaptic plasticity #Research
10:53am September 22nd 2014 via Hootsuite
AB: Developed a cre-lox knock-out Thorase mouse, with a frozen receptor, similar to cocaine response #ResearchFest
10:51am September 22nd 2014 via Hootsuite
AB: (Chen 2008 Neuron reference: http://t.co/CphahBn0n5 about persistent LTP) #ResearchFest
10:49am September 22nd 2014 via Hootsuite
AB: Ex: Single dose of cocaine changes LTP for 5d, shown as long as 3mo. Dopamine stim. - only a few days. #ResearchFest
10:48am September 22nd 2014 via Hootsuite
AB: Drugs of abuse change responses; long-term potentiation of dopamine neurons; DOA's do change potentiation #ResearchFest
10:46am September 22nd 2014 via Hootsuite
AB: Talking about dopamine: 'the center of my universe'; most fundamental Schiz, Parkinsons, ADHD, learning memory, abuse #ResearchFest
10:44am September 22nd 2014 via Hootsuite
Next: Dr. Antonello Bonci, Sci Dir NIDA "Optogenetic approaches to understanding substance use disorders" #ResearchFest
10:43am September 22nd 2014 via Hootsuite
(FARE award winners recognized per-Institute. Great work, well deserved!) #ResearchFest
10:41am September 22nd 2014 via Hootsuite
Lucie Lowe, introd. to the Fellows Award for Res Excellence: There are about 4,000 post-docs in the intramural NIH #ResearchFest
10:32am September 22nd 2014 via Hootsuite
MT @irpatnih: Dr. Collins: #Cancer #immunotherapy breakthroughs of Dr. Rosenberg http://t.co/opNl0r3K80 #ResearchFest http://t.co/gAJslgRLu4
10:27am September 22nd 2014 via Hootsuite
FC: The NIH intramural program in 10y; gave a plug @NIHDirector on Twitter and pointed to his blog http://t.co/pyg42pCM8e #ResearchFest
10:25am September 22nd 2014 via Hootsuite
FC: Reviewing the peer-review process to examine fairness; major new grant programs (BUILD for diversity, NRMN mentoring, CEC) #ResearchFest
10:23am September 22nd 2014 via Hootsuite
FC: 'We need to do a better job to make biomedical research more appealing' to encourage under-rep'd groups #ResearchFest
10:21am September 22nd 2014 via Hootsuite
FC: Major oppotrunity: preparing a diverse and talented biomedical research workforce. Encouraging early-stage researchers #ResearchFest
10:20am September 22nd 2014 via Hootsuite
FC: CAR T-cell therapy for ALL: illus. with a child named Phineas, starting Kindergarten. #ResearchFest
10:19am September 22nd 2014 via Hootsuite
FC: Science breakthrough of the year '13: Cancer Immunology, Steve Rosenberg's work (Yuzuki blog: http://t.co/J3ezCxpsos ) #ResearchFest
(Director's blog post from Sept 18 on the topic of bacterial resistance: http://t.co/l8piL264cn ) #ResearchFest
10:17am September 22nd 2014 via Hootsuite
FC: Adoption of NGS, Nat'l db of resistant pathogens, $20M prize via NIH/BARDA for better Dx #ResearchFest
10:16am September 22nd 2014 via Hootsuite
FC: Mentioned Julie Segre's work on battling antibiotic resistance in real-time. Annc Sept 18, nat'l strategy to combat #ResearchFest
10:15am September 22nd 2014 via Hootsuite
FC: May add schizophrenia to the list, AMP moving faster than expected #ResearchFest
10:13am September 22nd 2014 via Hootsuite
FC: Accelerating Medicines Partnership - for a 3 disease areas (T2D, Alz., RA) Pharma / NIH collab. http://t.co/m7h2AhNoJZ #ResearchFest
FC: Big Data to Knowledge website: http://t.co/AsFsvlcTvI #ResearchFest
10:11am September 22nd 2014 via Hootsuite
FC: BD2K is another: "Big Data to Knowledge" a 6-year initiative; est. of centers of excellence; facilitate tools. Award in 2w #ResearchFest
10:10am September 22nd 2014 via Hootsuite
FC: First $46M BRAIN opportunities awarded 'soon', many of the first ones technology development #ResearchFest
10:09am September 22nd 2014 via Hootsuite
FC: High-priority research areas: from fundamental principles to advancing human neuroscience, to application #ResearchFest
Francis Collins' intro comments at #ResearchFest Points out NIH-funding of recent Lasker Awardees; today talking about the BRAIN initiative
10:07am September 22nd 2014 via Hootsuite
Before F.Collin’s talk at today’s @NIH #ResearchFest ‘The Era of the Brain’ Sept 22-24 http://t.co/kkdWcTfgdw
10:03am September 22nd 2014 via Hootsuite
RT @NCCAM: Today at 10am in Masur Aud., #NIH #ResearchFest’s: “The Era of the #Brain” w/ Dr. Collins & award-winners: http://t.co/6pFnyD
9:56am September 22nd 2014 via Hootsuite
RT @fwpharma: BREAKING NEWS: Merck KGaA to buy Sigma-Aldrich for $17 billion http://t.co/LsKm666XCx #pharma #health
8:50am September 22nd 2014 via Hootsuite
RT @KevinADavies: Calico, Editas, Juno among the 2014 @FierceBiotech #Fierce15 "the coolest kids in school" http://t.co/b2xZrPc8M5
RT @GdnHigherEd: Fewer than 0.5% of #science PhDs become professors, but majority pursue careers outside academia http://t.co/BFbMDMRlhF
5:55pm September 21st 2014 via Hootsuite in reply to
RT @conradhackett: 1992: This photo of a science rock band was first image uploaded to web http://t.co/6gL7w6F1Cr http://t.co/22aN2gg4cO
4:40pm September 21st 2014 via Hootsuite in reply to
RT @rvaughnmd: Will US Health Care Follow in China’s Bloody Footsteps? http://t.co/4B3FAwgvCi via @thedailybeast
3:40pm September 21st 2014 via Hootsuite in reply to
RT @EricTopol: The science of sharing science http://t.co/wF1ovlVyVx Note how health, life science, and genetics fare http://t.co/Bg4oU8OK62
8:00am September 21st 2014 via Hootsuite
