Opportunity costs RT @TheAtlantic: Study: More time online means less time socializing, studying, and sleeping http://t.co/okJZDVajKd
3:25pm October 28th 2013 via Hootsuite in reply to
RT @KirkDBorne: Are you thinking of leaving science to be an entrepreneur? Elon Musk on why an MBA is a bad idea: http://t.co/1saFEJpKbS
1:25pm October 28th 2013 via Hootsuite
RT @NIHDirector: #NIH has listened to concerns about peer review delays caused by the regrettable shutdown. New plan: http://t.co/P44R2bqCOv
12:25pm October 28th 2013 via Hootsuite
RT @MichaelPellini: Our understanding of lung cancer continues to evolve. http://t.co/bafdrUo8Ax
11:25am October 28th 2013 via Hootsuite
RT @SallyRideSci: “…public education is still fundamentally rooted in the industrial revolution that spawned it.” http://t.co/hN2k3OMk3y
10:25am October 28th 2013 via Hootsuite
RT @vickyyyf: BBC News - Alzheimer's insight from DNA study http://t.co/b3q7eftcG7
9:25am October 28th 2013 via Hootsuite
:) RT @Pogue: Ohio State marching band’s amazing tribute to blockbuster movies…state-of-the-art marching! http://t.co/cUQjUD4dta
8:25am October 28th 2013 via Hootsuite
On a typical passenger flight, a human pilot holds the controls for a grand total of just 3 minutes http://t.co/tVzf0vuvy0 HT @EthicalLens:
7:25am October 28th 2013 via Hootsuite
Respect for C. Hadfield (astronaut) RT @hootsuite: A lifetime of achievement, most recently on social media: http://t.co/WasBaHwCC0
6:25am October 28th 2013 via Hootsuite in reply to
Looking at RNA-seq data RT @KatherineMejia: "Single-cell genomics: taking noise into account" http://t.co/nJx6HDg7ft
5:20am October 28th 2013 via Hootsuite in reply to
'It is biology for the Google set: unsentimental, joyfully technophilic & boundlessly optimistic' Nature ($) http://t.co/ZDurS3vFKu
4:20am October 28th 2013 via Hootsuite
RT @airandspace: Have plans for next Saturday? The Museum in DC where @Cmdr_Hadfield will be signing his new book: http://t.co/ssrxQGxhDR
6:35pm October 27th 2013 via Hootsuite in reply to
Replicating only 6 / 53 studies RT @mbeisen: Science has lost its way, at a big cost to humanity by @hiltzikm http://t.co/PbAh6Ivy29
5:40pm October 27th 2013 via Hootsuite in reply to
RT @girlscientist: Spkr shows slide 20 of this: http://t.co/B8uq3FeN36 which I do not get yet. NGS data exceeds patient limits? #ASHG2013
6:30pm October 26th 2013 via Hootsuite in reply to
RT @moorejh: Must read paper by Orjan Carlborg on the limits of statistical theory for analysis of #genomics data http://t.co/tmmHGYIfXH
6:25pm October 26th 2013 via Hootsuite in reply to
RT @RobertFreimuth: C.Eng: Baylor clinical WES - IF in 4.6% of patients, only 55% in the genes on the ACMG list #ASHG2013
5:25pm October 26th 2013 via Hootsuite in reply to
RT @EpgntxEinstein: Les Biesecker (NHGRI): Somatic mosaicism causing overgrowth syndrome, most dramatic phenotypes likely to see #ASHG2013
4:30pm October 26th 2013 via Hootsuite in reply to
"Many of our new gadgets... often keep keep us from experiencing these face-to-face situations" WSJ http://t.co/m6SjHDoNFA
2:40pm October 26th 2013 via Hootsuite
Anki Drive isn't just a car racing game, it's an iOS-based robotics platform - Engadget http://t.co/uNZ0xdrQ52
1:50pm October 26th 2013 via Hootsuite
RT @paulblaser: How to read and understand a scientific paper: a guide for non-scientists http://t.co/ii3nswVtzo via @JenniferRaff
11:40am October 26th 2013 via Hootsuite in reply to
Wordpress 3.7 released. | TNW http://t.co/iNQOfBchYj
10:40am October 26th 2013 via Hootsuite
RT @harrymccracken: Here’s my review of Anki Drive (fun, technologically amazing, wish the battery life was longer). http://t.co/OBeVLwkD18
7:40am October 26th 2013 via Hootsuite in reply to
@harrymccracken Nice review - did you mean 'feet' instead of 'inches'? (8.5 inches x 3.5 inches seems awfully small...)
8:00pm October 25th 2013 via Hootsuite in reply to
RT @bionanogenomics: Introducing our new high-throughput IrysChip V2. 15x inc. in data for detection of human SV’s. http://t.co/7jfIzL0CXv
6:10pm October 24th 2013 via Hootsuite
RT @drgitlin: @matthewherper @NMNH eh, SI’s mag had an article about DNA and genomics recently and didn’t even plug the exhibit. So strange.
5:10pm October 24th 2013 via Hootsuite in reply to
RT @AllSeq: Really great post by @erlichya on @nanopore's sample prep http://t.co/4mKljSmfBh #ASHG2013
4:11pm October 24th 2013 via Hootsuite
RT @Berci: Genomics Pioneer Craig Venter Envisions Future of Synthetic Life http://t.co/yTJIexVOoC #genomics #future
3:11pm October 24th 2013 via Hootsuite
Geraghty: Problem with MHC, haplotypes, extended linkage disequil. DR, DQ alleles identical. #ASHG2013
2:50pm October 24th 2013 via Hootsuite
Geraghty: Challenge Type-1 Diabetes. 1973 paper MHC-I or -II not resolved. #ASHG2013
2:48pm October 24th 2013 via Hootsuite
Geraghty: 10y.o. using Fosmids for 40kb inserts, sequenced 'Killer Ig-like receptors' #ASHG2013
2:47pm October 24th 2013 via Hootsuite
Speaker: D Geraghty Complete resequencing of ext. genomic regions using fosmid targeting and PacBio's long-read sequencing tech #ASHG2013
2:45pm October 24th 2013 via Hootsuite
DeLuca: Conclude: GEM attractive for eQTLs, ASE; TH2 preferred for splicing-based eQTLs #ASHG2013
2:31pm October 24th 2013 via Hootsuite
DeLuca: Conclude: 'Different aligners are optimal for different applications'. Tophat, GEM have reas comput costs. #ASHG2013
2:30pm October 24th 2013 via Hootsuite
DeLuca: Computational perf: Star alignment speed shines, orders of mag. better. Converted to $: Stars is 'incred cheap' in AWS #ASHG2013
2:28pm October 24th 2013 via Hootsuite
DeLuca:Split reads, adipose TH2 leads, sim. data TH2 again leads, two-split reads (3-exon spans), TH1/2 much better #ASHG2013
2:27pm October 24th 2013 via Hootsuite
DeLuca: Looking at FP rate, GEM also led in comparison. In/dels for simulation - also GEM leads. Insertions still challenging #ASHG2013
2:26pm October 24th 2013 via Hootsuite
DeLuca: TopHat1, TH2, Star and GEM compared; GEM had better call rate for non-ref bases. #ASHG2013
2:25pm October 24th 2013 via Hootsuite
DeLuca: Referred to Grant et al as a nice place to start, only from 2011. PubMed: http://t.co/VDHvpcWE0U #ASHG2013
2:23pm October 24th 2013 via Hootsuite
DeLuca: Challenged by lack of 'ground truth', spectrum of parameters. Wanted obj comparisons #ASHG2013
2:20pm October 24th 2013 via Hootsuite
DeLuca: GTEx looks at eQTLs, ASE and splice site QTLs; wanted to align, accommodate split reads, accurate and tolerate var's #ASHG2013
2:19pm October 24th 2013 via Hootsuite
Up next: D. DeLuca, Broad Inst., on RNA-seq aligners for QTL and ASE analysis for GTex. #ASHG2013
2:17pm October 24th 2013 via Hootsuite
About research in PNAS RT @lindaavey: Major Alzheimer's risk factor linked to red wine target: http://t.co/VFyTSaL42P
2:11pm October 24th 2013 via Hootsuite in reply to
Quinones: Maintains a database of sequenced HIV strains, assesses viral load via RT-PCR, calc. intrinsic error rate of seq. #ASHG2013
1:48pm October 24th 2013 via Hootsuite
Quinones: 'DeepGen': an all-inclusive test. Complex mapper to account for the thousands of highly variable HIV strains. #ASHG2013
1:46pm October 24th 2013 via Hootsuite
Quinones: 'So it came down to cost'. Turnaround time is vital too for any clinical setting. #ASHG2013
1:44pm October 24th 2013 via Hootsuite
Quinones: Fig from PLoS paper, he believes that 'Hi-Q will be a game-changer'. Paper concl. "no difference in det. HIV-1 tropism' #ASHG2013
1:43pm October 24th 2013 via Hootsuite
Quinones: Listed publications across vendors. He compared all four platforms on HIV-1, published in PLoS http://t.co/WwwhVxmb0s #ASHG2013
1:42pm October 24th 2013 via Hootsuite
Quinones: Doing 3 or 4 different drug-resistance tests may require multiple boxes and assays for HIV. With NGS: a single method. #ASHG2013
1:41pm October 24th 2013 via Hootsuite
Quinones: HIV-1 minority variants - using allele-specific PCR or OLA for drug-resistant variants. Until now - 454-based #ASHG2013
1:39pm October 24th 2013 via Hootsuite
Quinones: Since Sanger is only 20% sensitive to heterogeneous samples, wanted a deep-sequencing approach. #ASHG2013
