Reynolds: Looking at P450 in 15K samples, with self identified ethnicity. Goal to look at drug efficicacy. #IonWorld2013
2:09pm October 21st 2013 via Hootsuite
Thomas Reynolds American Int'l Biotechnology (AIBiotech) on pharmacogenomics testing up next at #ionworld2013
2:07pm October 21st 2013 via Hootsuite
Photo of William Strauss (Cynvenio) at #IonWorld2013 http://t.co/WakKmFZ4eD
2:06pm October 21st 2013 via Hootsuite
Strauss: Used AmpliSeq RNA to detect fusion events in CTCs #IonWorld2013
2:03pm October 21st 2013 via Hootsuite
Strauss: Recovery and numeration of cells:single and clusters of cells can be examined microscopically #IonWorld2013
1:53pm October 21st 2013 via Hootsuite
Strauss: Samples stable at RT for 4d. Proprietary chip, robot uses immunomagnetic separation tech. #IonWorld2013
1:52pm October 21st 2013 via Hootsuite
Strauss: Cynvenio makes a platform for rapid extraction of rare cells from whole blood. 'LiquidBiopsy' collection kit. #IonWorld2013
1:51pm October 21st 2013 via Hootsuite
Strauss: Counting CTCs can show prognostic value. Br, C-R, Prostate cancers #IonWorld2013
1:47pm October 21st 2013 via Hootsuite
Strauss: Circulating tumor cells (CTCs) may initiate metastasis, could be integral in tumor staging, disease monitoring #IonWorld2013
1:46pm October 21st 2013 via Hootsuite
William Strauss, Cynvenio Biosystems: Capturing circulating tumor cells then somatic detection via the AmpliSeq hotspot panel. #IonWorld2013
1:45pm October 21st 2013 via Hootsuite
A Felton: AmpliSeq RNA panels assay for ALK, RET and ROA1 fusion events. Single-tube, Ambion, FALCON and OncoNetwork #IonWorld2013
1:43pm October 21st 2013 via Hootsuite
E Topol: Q&A: Cases are for penetrant diseases; we need to understand function of modifier genes. Need millions of samples. #IonWorld201
1:36pm October 21st 2013 via Hootsuite
E Topol: Scripps Health website for background on the Wellderly study on the genetics of healty aging. #IonWorld2013 http://t.co/qTfVuLhcWs
1:34pm October 21st 2013 via Hootsuite
E Topol: Health Affairs reference on the economic benefit of delayed aging ($) #IonWorld2013 http://t.co/WhWCc87qEs
1:33pm October 21st 2013 via Hootsuite
E Topol: Angelina Jolie is the exemplar case of democratizing medicine. 'She selected everything'. Angelina effect = great. #IonWorld2013
1:31pm October 21st 2013 via Hootsuite
E Topol: Healthspan - discussion of the Scripps Wellderly study, genetics of healthy aging. #IonWorld2013
1:30pm October 21st 2013 via Hootsuite
E Topol: Mention of Genia's plan to develop a mobile handheld sequencer for pharmacogenomics. #IonWorld2013
1:29pm October 21st 2013 via Hootsuite
E Topol: Nature Nanotechnology reference - capture of cell-free DNA via graphene nanosheets http://t.co/pgSVvSyyQz #IonWorld2013
1:28pm October 21st 2013 via Hootsuite
E Topol: MOOM - Massively Open Online Medicine, patients sharing their information globally, subtypes of disease #IonWorld2013
1:27pm October 21st 2013 via Hootsuite
E Topol: Cell-free DNA may be representative to target cancer. Now better ways to capture (nanosheets in Nature Nano 27 Sept) #IonWorld2013
1:26pm October 21st 2013 via Hootsuite
E Topol: Foundation Med.: 2221 pts, 287 genes, 1134x coverage, 118 FFPE confirmed. 'Actionable' NBT ($) #IonWorld2013 http://t.co/SuE6cbNTKI
1:23pm October 21st 2013 via Hootsuite
E Topol: Science paper review from Mar 2013 Vogelstein #IonWorld2013 Science ($) http://t.co/B3n8Z1zuVe
1:21pm October 21st 2013 via Hootsuite
E Topol: Cancer: TCGA publ. last week in Nature, remarkable 'GIS of Cancer'. Protein, microRNA, etc. understanding pathways #IonWorld2013
1:20pm October 21st 2013 via Hootsuite
E Topol: (At present - about 100K individuals sequenced.) #IonWorld2013
1:18pm October 21st 2013 via Hootsuite
E Topol: ~2K variants in CFTR - when should everyone be sequenced for rare variant characterization? 2 or 3 mil. individuals #IonWorld2013
E Topol: Disease prevention - risk of AMD (leading cause of blindness) increasing risk 23x via genetic tests #IonWorld2013
1:16pm October 21st 2013 via Hootsuite
E Topol: Lilly's genome: a molecular dx made, after >$1M spent. ADCY5 dysfunction, led to treatment. #IonWorld2013
1:15pm October 21st 2013 via Hootsuite
E Topol: 'Spectacular' paper in NEJM about exome sequencing of rare disorders. http://t.co/6X0gsGyueI #IonWorld2013
1:14pm October 21st 2013 via Hootsuite
E Topol: Mentions 23andMe, Counsyl, Genepeeks; also the four NIPT companies (>100K tests done by 4 providers) #IonWorld2013
1:11pm October 21st 2013 via Hootsuite
E Topol: Brought up this Sept WSJ editorial about medical education. http://t.co/8h3AolRqdN #IonWorld2013
1:08pm October 21st 2013 via Hootsuite
E Topol: Stethoscopes are relics; now have a hi-res ultrasound that fits into a pocket. #IonWorld2013
1:07pm October 21st 2013 via Hootsuite
E Topol: Other apps for healthcare: diabetes and cancer apps. Imaging too - hooked up to an otoscope (another Colbert clip) #IonWorld2013
1:05pm October 21st 2013 via Hootsuite
E Topol: Colbert Report clip: a heart attack ringtone. "Would you like 20% off on caskets?" #IonWorld2013
1:04pm October 21st 2013 via Hootsuite
E Topol: Acute myocardial infarction - connecting an RNA signal from circulating cells to detect an oncoming heart attack #IonWorld2013
1:03pm October 21st 2013 via Hootsuite
E Topol: Ave. car has 400 sensors, smartphone has 10, humans have zero. #IonWorld2013
1:02pm October 21st 2013 via Hootsuite
E Topol: Demonstrating a realtime glucose monitor. IonWorld2013 http://t.co/d64RnjKd23
1:01pm October 21st 2013 via Hootsuite
E Topol: Review of his book: the best exemplar of the convergence of the digitization of medicine is semiconducting sequencing #IonWorld2013
12:59pm October 21st 2013 via Hootsuite
E Topol: 'The problem with medicine today is that it is done at the population level' #IonWorld2013
12:55pm October 21st 2013 via Hootsuite
Eric Topol: Begins by asking 'how many are on Twitter'? #IonWorld2013
12:53pm October 21st 2013 via Hootsuite
RT @kayellbe: Curious about details of the "Hi-Q" enzyme mentioned by MStevenson. 420bp sequences at quality score >30. #ionworld2013
RT @GlobalEcoGuy: Antibiotic crisis: we're already there. And livestock use might be the biggest reason. http://t.co/8Z3pW7H8au
11:50am October 21st 2013 via Hootsuite in reply to
RT @Awesomics: World's largest gathering of human geneticists: 6.5K attendees, 200 co's ➞ Oct 22-26 Boston http://t.co/iiuoodxbfe #ASHG2013
10:50am October 21st 2013 via Hootsuite in reply to
.@ScienceNewsOrg Loved learning about the brain's glymphatic system: the hypothesis that sleep 'cleans' it of toxins. http://t.co/SzKIRj5ffm
10:41am October 21st 2013 via Hootsuite in reply to
Claritas, Lockheed and Life Technologies awarded $9M from the VA as part if the Million Veteran Program. http://t.co/UVXik0frpk
10:20am October 21st 2013 via Hootsuite
#ionworld2013 in Boston ready to start. And BGI announces a purchase of 37 Ion Protons | Yahoo Finance http://t.co/SjLI8TKRiD
10:12am October 21st 2013 via Hootsuite
353 methylation markers, on research in Genome Biol. RT @guardianscience: Scientists discover DNA body clock http://t.co/EDwI27o0c6
9:50am October 21st 2013 via Hootsuite in reply to
RT @ruskin147: http://t.co/Oetof5dTwn Survey shows risky web habits of Primary school children
8:52am October 21st 2013 via Hootsuite in reply to
By EU MetaHIT RT @WvSchaik: '43% of species abundance and 58% of richness cannot be captured by (current methods)' http://t.co/zGiYiKsJg3
7:50am October 21st 2013 via Hootsuite in reply to
TIL that deer in the US were hunted to near-extinction: 350K in 1900. Now at >30M, a huge conservation challenge. http://t.co/gzpYvbly6q
6:50am October 21st 2013 via Hootsuite
According to the WSJ, standalone MP3 players went from 180M in 2010 to 90M in 2013. Navi devices from 40M to 30M.
5:50am October 21st 2013 via Hootsuite
