Recent Tweets Page 92

Bustamante: #AGBTph18 Then health coins change value, as pt performs agreed-on actions...

9:17pm September 6th 2018 via Twitter Web Client

Bustamante: #AGBTph18 Apple is there today; ResearchKit w/postpartum depression. EHR on their phones w/CareKit.

9:14pm September 6th 2018 via Twitter Web Client

Bustamante: #AGBTph18 Today we are focused on EHR, 'Omics, imaging, outcomes, pathology, Rx. The new world - pts bringing their data w/them

9:11pm September 6th 2018 via Twitter Web Client

Bustamante: #AGBTph18 20% of GDP is devoted to 'sick care'; so tech co's will go after healthcare. 'They are here.'

9:10pm September 6th 2018 via Twitter Web Client

Bustamante: #AGBTph18 The innovator's dilemma, disruptive technologies. 'Data is the most valuable resource' https://t.co/s9ClgCrYKh

9:09pm September 6th 2018 via Twitter Web Client

Bustamante: #AGBTph18 Shows May '18 GenomeWeb - Color and FH Foundation https://t.co/qMrKnZ7bGT

9:07pm September 6th 2018 via Twitter Web Client

Bustamante: #AGBTph18 63% of high-risk FH pts cannot get approval. Goes through flowchart, lipid clinic n=20,434; FH-pos n=582

9:04pm September 6th 2018 via Twitter Web Client

Bustamante: #AGBTph18 Top 20% takes up 81.2% of the budget. 70% via employer.

9:03pm September 6th 2018 via Twitter Web Client

Bustamante: #AGBTph18 '06 NEJM https://t.co/ClUS3vkb6H Problem: Repatha is $12K/yr. '$500B increase'. Per-capita - in '10 $8.4K

9:02pm September 6th 2018 via Twitter Web Client

Altshuler #AGBTph18 3 Nobels for cholesterol; all before statins approved etc. Length of time to benefit pts - the goal is to speed it up

8:39pm September 6th 2018 via Twitter Web Client

Altshuler #AGBTph18 Two different medicines developed at Aurora: '11 ref https://t.co/CXatqCVfmw Shows PhIII results https://t.co/qR5sLlNI2r

8:30pm September 6th 2018 via Twitter Web Client

Altshuler #AGBTph18 50% reduction in death, long-term, real-world data for Ivacaftor. Problem: only a 10% fraction w/spec mutation

8:27pm September 6th 2018 via Twitter Web Client

Altshuler #AGBTph18 Ivacaftor's mechanism; G511D causes defect in channel gating activity of CFTR, and ivacaftor opens it up.

8:24pm September 6th 2018 via Twitter Web Client

Altshuler #AGBTph18 '89 Science https://t.co/vYSHUF1CQY Lodish quote: "I wouldn't bother" w/small molecule approach

8:22pm September 6th 2018 via Twitter Web Client

Altshuler #AGBTph18 Points to this '13 ref https://t.co/i1PvyDBclW and each author w/in 3 y in industry to help on the road less travelled

8:19pm September 6th 2018 via Twitter Web Client

Altshuler #AGBTph18 Most cases 'the biology will be new' and thus need to discover and develop innovative medicines.

8:15pm September 6th 2018 via Twitter Web Client

Altshuler #AGBTph18 Ivacaftor synthesized in '04, approved w/Lumacaftor in '15. A 20-year journey. '07 Lumacaftor candidate ID'd '07

8:12pm September 6th 2018 via Twitter Web Client

Altshuler #AGBTph18 Presents a timeline of CF: '89 gene discovered; function in the '90's; in '99 Aurora/Vertex SD starts work.

8:11pm September 6th 2018 via Twitter Web Client

Altshuler #AGBTph18 Points out Bill, from 2015 at the White House SOTU address, in medical school, and a CF pt. on a Vertex drug

8:10pm September 6th 2018 via Twitter Web Client

Altshuler #AGBTph18 Scientists' dedication is 'on-par w/academia, but no one knows who they are'. Rx 'magically appears'.

8:09pm September 6th 2018 via Twitter Web Client

Altshuler #AGBTph18 Second title: Humanizing drug discoery. Human genetics/genomics is 'unmatched at getting at human biology'.

8:08pm September 6th 2018 via Twitter Web Client

David Altshuler (CSO Vertex) Diverse perspectives on Genomic Medicine #AGBTph18

8:07pm September 6th 2018 via Twitter Web Client

Eric Green, director of NHGRI giving the #AGBTph18 introduction. https://t.co/YPntDtqCdb

8:03pm September 6th 2018 via Twitter for iPhone

Quantapore Working Towards Commercialization of Optical Nanopore Sequencing Tech | GenomeWeb ($) https://t.co/vqTRSdBycL

11:36am September 5th 2018 via Hootsuite Inc.

Radical open-access plan could spell end to journal subscriptions | Nature https://t.co/AEMimT6z4b

10:40am September 5th 2018 via Hootsuite Inc.

New post: Two Pore Guys single-molecule diagnostic platform update https://t.co/vprvahIYGC

12:08pm September 4th 2018 via WP to TWTR on Yuzuki.org

10x Genomics Acquires Epinomics | GenomeWeb https://t.co/rq5BNEvQ0O

3:24pm August 28th 2018 via Hootsuite Inc.

Illumina Secures China National Drug Administration Clearance for MiSeqDx System | GenomeWeb https://t.co/fqUVN2ICis

2:44pm August 28th 2018 via Hootsuite Inc.

A CRISPR cure for Duchenne muscular dystrophy is closer after a trial in dogs - MIT Technology Review https://t.co/0vM9fV7qSa

6:55am August 27th 2018 via Hootsuite Inc.

Akonni Biosystems Scores $3M NIH Grant for POC Dx Platform, Drug-Resistant TB Assay | GenomeWeb https://t.co/lU4fbBEVKK

10:05am August 24th 2018 via Hootsuite Inc.

Haim #NGSDx18 The walls between gov't org's, gov't funding and VC's are breaking down.

12:44pm August 23rd 2018 via Twitter Web Client

DeWinter #NGDx18 Plenty of different kinds of risk, new models of reimbursement just adds another layer, so thus no innovation there.

12:38pm August 23rd 2018 via Twitter Web Client

Merkeley #NGDx18 To solve sepsis, they see themselves as partners with Medicare/Medicaid - coordinating with CMS/CDC and industry

12:29pm August 23rd 2018 via Twitter Web Client

DeWinter #NGDx18 Does it make sense to accept money from GE? The investment Q to answer.

12:26pm August 23rd 2018 via Twitter Web Client