February 2015

O'Rourke:Need to go beyond trad. recruitment. Consult with existing cohort participants. Low-cost to participate #PMINetwork

10:00am February 11th 2015 via Hootsuite

O'Rourke:Allow for change of values over time in addition to levels of participation. Families? Governance will be necessary. #PMINetwork

9:58am February 11th 2015 via Hootsuite

O'Rourke:Think of value: Framingham framed in a sense of 'belonging' to something. Individual values/pref's respected #PMINetwork

9:56am February 11th 2015 via Hootsuite

O'Rourke:Toolkis between participants & providers - what's in it for everyone; financial considerations; confirmatory tests #PMINetwork

9:55am February 11th 2015 via Hootsuite

O'Rourke:Research/clinical is no longer 'boundary', rather it is 'intersection'. All parties - incl. providers - need involvment #PMINetwork

9:54am February 11th 2015 via Hootsuite

O'Rourke:New landscape - needs to be inclusive, flexible. 'What is "it"?' Specific goals? Kinds of participation? #PMINetwork

9:53am February 11th 2015 via Hootsuite

Pearl O'Rourke: "Participant engagement, data privacy, and novel ways of returning information to participants: #PMINetwork

9:51am February 11th 2015 via Hootsuite

RT @girlscientist: Agreed with @NIMHgov's Tom Insel: let's think about different ways to do cohorts, and include children/families! #PMINet…

9:44am February 11th 2015 via Twitter Web Client

Boerwinkle:Q:Different cohort design (i.e. children vs. parents) A:It won't be Framingham 'on steriods' necessarily. Later topic #PMINetwork

9:42am February 11th 2015 via Hootsuite

Boerwinkle:Q:Early discovery vs. building a resource? A:We need both; disclosed to both participants and researchers. #PMINetwork

9:40am February 11th 2015 via Hootsuite

Boerwinkle:We shouldn't be too gene- or genome-focused; need a wider focus, also wide on phenotypes as well #PMINetwork

9:37am February 11th 2015 via Hootsuite

Lauer: Mechanism for rapid, efficient randomized trials; an enormous 'scientific commons'. Eric Boerwinkle acknowledged #PMINetwork

9:32am February 11th 2015 via Hootsuite

Lauer:Framingham was the 1st time 'elevated risk' term was used, but long time to evaluate. Big, audacious ideas now accelerated #PMINetwork

9:31am February 11th 2015 via Hootsuite

Lauer:Possible to change the dynamic between participants and researchers; a two-way relationship. #PMINetwork

9:29am February 11th 2015 via Hootsuite

Lauer:Gov't coordination 'is huge'. Either can accelerate or stymie progress. Key goal: advise on policy, mgmt, direction #PMINetwork

9:27am February 11th 2015 via Hootsuite

Lauer:Technology second concern; rapidly evolving, can leverage what is now, and grow with it. Bidirectional internet, mobile... #PMINetwork

9:25am February 11th 2015 via Hootsuite

Lauer:First concern: Expense, time and feasibility: key point is not from scratch. Existing data, recruitment, data, methods #PMINetwork

9:24am February 11th 2015 via Hootsuite

Lauer: Lays out a key feature: to get major communication across cohort studies. Illust. w/ Dr. Dover / Framingham as a model #PMINetwork

9:23am February 11th 2015 via Hootsuite

Next up: Mike Lauer "Building a consortium of cohorts: cohort identification and participant recruitment" #PMINetwork

9:21am February 11th 2015 via Hootsuite

Collins:'The success of our enterprise depends on... the best ideas here' #PMINetwork

9:16am February 11th 2015 via Hootsuite

Collins: Need expansion of working groups within #PMINetwork Coordinate with WH and other agencies. Homepage http://t.co/VVMtlXXfcu

9:16am February 11th 2015 via Hootsuite

Collins:Lays out goals for meeting. Planning in FY15, begin building FY16. 4 workgroups here: http://t.co/rHH1Qofi29 #PMINetwork

9:15am February 11th 2015 via Hootsuite

Collins:In 10y: happy ending, no diabetes-related complications #PMINetwork

9:12am February 11th 2015 via Hootsuite

Collins:In 2y: has real-time blood glucose tracking via wireless sensors. 5y:Finds out abt new therapy with precise dosage #PMINetwork

9:12am February 11th 2015 via Hootsuite

Collins: Gives an example of what precision med. might look like for T2D: sample DNA, view health/rsrch data via smartphone #PMINetwork

9:10am February 11th 2015 via Hootsuite

Collins: 4th early win: Oppy to evaluate large array of mHealth technologies for mgmt of chronic disease #PMINetwork

9:09am February 11th 2015 via Hootsuite

Collins:Third - concept of Resilience - need large datasets. Behind the Bench @iontorrent post here: http://t.co/4CionHl06N #PMINetwork

9:08am February 11th 2015 via Hootsuite

Collins: Another success marker: new targets by ID loss-of-function mutations protective (PCSK9 for CV, SLC30A8 for T2D) #PMINetwork

9:07am February 11th 2015 via Hootsuite

Collins: What early success might look like to insure ongoing support: a real test of PGx - does it work at scale? Real-world? #PMINetwork

9:06am February 11th 2015 via Hootsuite

Collins: Not 'patients', rather 'participants' - must be involved in the study design and receive data back. #PMINetwork

9:04am February 11th 2015 via Hootsuite

Collins: Mentions the liquid biopsy as one of the promising areas of personalized medicine. >1M volunteers... #PMINetwork

9:03am February 11th 2015 via Hootsuite

RT @girlscientist: OK I'll say it: I got Francis to write that commentary in 2004 and I stand by it. We were just ahead of our time. #PMINe…

9:00am February 11th 2015 via Twitter Web Client

RT @gabecasis: Francis recalling his 2004 Nature paper. http://t.co/UP0iyMz6iv #PMINetwork But compute, sequencing, mobile, EMR, make it ea…

9:00am February 11th 2015 via Twitter Web Client

RT @claudiawilliams: The time is right #PMINetwork http://t.co/q9dFO7FKUM

8:59am February 11th 2015 via Hootsuite

Amazing attendee list RT @NIHDirector: A lot of interest in the #PMINetwork on Feb 11&12. Here’s how you can link in: http://t.co/tY1uLC

8:30am February 11th 2015 via Hootsuite

RT @NIHDirector: A lot of interest in the #PMINetwork on Feb 11&12. Here’s how you can link in: http://t.co/tY1uLCgs7n

8:04am February 11th 2015 via Hootsuite

In case you were wondering what @iontorrent was planning for #AGBT15, here you go: http://t.co/3wskjhRak4 75 hours of NGS goodness!

8:00am February 11th 2015 via Hootsuite

CoreGenomics: What can you read if you're new to NGS? http://t.co/62yC1yoHRb

6:35am February 11th 2015 via Hootsuite

Study Claims PCR from Primers Annealed in Parallel Orientation | GenomeWeb http://t.co/DnBTodt4D0

5:35am February 11th 2015 via Hootsuite

Even cockroaches have personalities | Science/AAAS http://t.co/fKF1xEmABy

4:15am February 11th 2015 via Hootsuite

I realize it's only Tuesday but still useful... RT @fixedopsgenius: 15 Questions to Ask Yourself Every Friday http://t.co/Yb1Aa6vlQ3

10:55pm February 10th 2015 via Hootsuite

J. Craig Venter Speaks About DNA and the Mysteries of Life - WSJ http://t.co/Arwj2JDg07

9:55pm February 10th 2015 via Hootsuite

RT @AppliedBio: The Road to POP-7 sequencing polymer. Watch now: http://t.co/x16Q3HpMH5 http://t.co/6Jkwtm173I

8:35pm February 10th 2015 via Hootsuite

RT @genome_gov: Check out NIH Director Francis Collins' newest blog on precision oncology. http://t.co/zLCG4WCF4M #cancer #precisionmedicine

7:50pm February 10th 2015 via Hootsuite

@TheAtlantic: Professor stripped of tenure over a blog post. http://t.co/3qn3EAmNwh http://t.co/WRXBX19V8V

6:35pm February 10th 2015 via Hootsuite

RT @AstroTerry: 5 years ago today, we docked with #ISS... #STS130 #Endeavour http://t.co/zr52Jw98Ds

5:05pm February 10th 2015 via Hootsuite