Bickmore #AGBT19 How do the enhancers act from a distance? '15 Trends Genet https://t.co/hBbjFHBNhT Mechanism - coh… https://t.co/g79qwupUkr
Bickmore #AGBT19 These sites where tissue-spec Transcription factors act, and mutations affect function. Shh - many… https://t.co/3N64QbsDXU
Bickmore #AGBT19 Also dosage sensitive - duplications of enhancers. Pierre Robin Sequence >1Mb from SOX9 transloc,… https://t.co/nPwKRaDj
Bickmore #AGBT19 De novo events in these areas can cause Mendelian disorders. Long list of diseases (i.e. Syndactyl… https://t.co/4VOs5z1eWl
Bickmore #AGBT19 There are 13 enhancers of Shh - many more expected to be discovered. 1M bp away; still in the co-l… https://t.co/eokNMFf6eE
Bickmore #AGBT19 Topologically-Active Domains - triangle-shaped regulatory domains of dev genes. Sonic Hedgehog (S… https://t.co/W8KByrxvTz
Bickmore #AGBT19 Shows imaging methods from '11 https://t.co/onEqOOPtN8 and Hi-C methods with Chr 2 (active) and Ch 2 (inactive)
Wendy Bickmore (The University of Edinburgh) #AGBT19 Spatial organization of the human genome
New post: The early days of spatial genomics at #AGBT19 https://t.co/y0Fzo6IML2
RT @nanostringtech: Special thank you to @DaleYuzuki for attending our #SpatialGenomics Summit yesterday at #AGBT19… https://t.co/wefe3meG0P
New post: NanoString’s Digital Spatial Profiling Microscope at #AGBT18
RT @mason_lab: Aviv Regev showing the cool, emerging landscape and tool box for spatial genomics, including @nanostringtech GeoDx #AGBT19 h…
RT @mason_lab: @hagentilgner getting ~400GB on the new @PacBio 8M ZMW SMRTcell, with 1-5 million CCS cDNA reads and <1% error rate. Lower
RT @tysonaclark: Wow. Apparently I tweeted a lot in 2017. Don’t think I’ll make the list this year at #AGBT19. Go @DaleYuzuki. https://t…