RT @TechCrunch: Theranos starts to agree to things https://t.co/91xT1sKEH6 https://t.co/dEDjeu01AX
8:39pm April 18th 2017 via Hootsuite
Startup 1Cellbio Inks Single-Cell Sequencing Collaboration With UCB | GenomeWeb https://t.co/wtIfAKYWjs
7:35pm April 18th 2017 via Hootsuite
Vela Diagnostics Expects CE Mark Soon for NGS-based HIV Drug Resistance Assay | GenomeWeb ($) https://t.co/vP1l7asvi8
7:10pm April 18th 2017 via Hootsuite
Thermo Fisher Scientific to Collaborate With University Hospital Basel on Companion Dx | GenomeWeb https://t.co/loZNFGjraa
6:10pm April 18th 2017 via Hootsuite
UC-Davis, Dovetail Genomics Approach Chromosome-Scale Assemblies for AgBio With Lettuce Genome | GenomeWeb https://t.co/LUc9J88cX2
5:10pm April 18th 2017 via Hootsuite
Stool donations in Cambridge? Just Pop On In | GenomeWeb https://t.co/kajIdRbtsD
4:05pm April 18th 2017 via Hootsuite
Singulex Closes $50M Debt Facility | GenomeWeb https://t.co/MQhjbCHYcd
3:32pm April 18th 2017 via Hootsuite
RT @SeraCare: Our very own @DaleYuzuki featured in @GENbio: #CTCs Can Make Better Samples Than Biopsies https://t.co/pBaTKVyfUi #TRICON #NG…
5:59pm April 15th 2017 via Hootsuite
Carvalho: Using a pillar system with functionalized surface. (Method still in development, unclear what surface treatment is) #MDxEU17
7:01am April 13th 2017 via Hootsuite
Carvalho: Optimized was non-chaotropic (glycine). 2nd approach is disposable PDMS, walks thru microfabrication of masks etc. #MDxEU17
6:57am April 13th 2017 via Hootsuite
Carvalho: Shows CNC router and PMMA plat w/machined patterns. Showed their experiments of chaotropic and non-chaotropic salts #MDxEU17
6:53am April 13th 2017 via Hootsuite
Carvalho: At bench scale, using silica and salt/pH. Microscale: several different approaches next. One is miniaturizing silica #MDxEU17
6:50am April 13th 2017 via Hootsuite
Carvalho: DNA is specific, durable, sensitive (if amplified), easy functionalization. Extract, amplify, detect #MDxEU17
6:45am April 13th 2017 via Hootsuite
Carvalho: Working on microTAS - total analysis system; fast, sensitive, 'in situ detection' for DNA analysis. #MDxEU17
6:44am April 13th 2017 via Hootsuite
Joana Carvalho (Iberian Nanotechnology Lab PT): Enabling technologies for cell-free DNA #MDxEU17
6:43am April 13th 2017 via Hootsuite
Leslie:Sensitivity shown down to 5% on the chip, where they are now. Able to show data from tumor samples as well #MDxEU17
6:39am April 13th 2017 via Hootsuite
Leslie: PIK3CA activating muts - 40% of breast ca, >75% of these muts are in 3 aa's. H1047/E545/E542. Using Intplex #MDxEU17
6:36am April 13th 2017 via Hootsuite
Leslie: #MDxEU17 Platform described in '10 Lab Chip https://t.co/nqyci4tVoj 12mL blood in single run; dilution req'd 1:1
Leslie: Working with Maiwenn Kerhoas and Med Res Scotland: microfluidics as a tool for cfDNA analysis. 10um channels#MDxEU17
6:34am April 13th 2017 via Hootsuite
Leslie: Mouse model of functionally-selective PTEN mutant. Next topic: applying microfluidics for improve non-invasive cancer dx #MDxEU17
Leslie: PTEN muts - mouse knock-in, single copy enough for normal activity. Homozygous mutant die in 9d embryos. #MDxEU17
6:32am April 13th 2017 via Hootsuite
Leslie: HER2 receptor 20% gene amplification. Downstream of PIP3 lipid - Akt, Btk, Rac, Arf GEFs#MDxEU17
6:30am April 13th 2017 via Hootsuite
Leslie: 10y of clinical trials 'have not gone well'; in breast cancer, 35% PTEN LoF, 40% PIK3CA specific pt mutations AKT1 6% #MDxEU17
6:29am April 13th 2017 via Hootsuite
Leslie: PTEN and Class I PI 3-K signalling numerous GF's, cytokines, ECM etc. - PTEN is a phosphatase on PIP3, convert to PI(4,5)P2 #MDxEU17
6:28am April 13th 2017 via Hootsuite
Nicholas Leslie (Heriot Watt Univ Scotland) A simple and robust real-time PCR method for PIK3CA mutations in breast cancer #MDxEU17
6:27am April 13th 2017 via Hootsuite
Whitchurch: "I talent scout for science for the military" fedbizopps will have DTRA funding opps #MDxEU17
5:31am April 13th 2017 via Hootsuite
Whitchurch: Shows photos from the 'current state' of in-field Dx and reduce time spent in 2nd-line care. #MDxEU17
5:29am April 13th 2017 via Hootsuite
Whitchurch: What about real-time biochemistry on the person? A check-engine light on a car - on a human? #MDxEU17
5:27am April 13th 2017 via Hootsuite
Whitchurch: Shows the first GPS in 1980 - a 26-lb, backpack. Shows first ECG in 1911. And Glucose meter in '45 #MDxEU17
5:26am April 13th 2017 via Hootsuite
Whitchurch: Military culture - they will fight 'until they are too sick to fight'. Thus to get in front of that - wearable #MDxEU17
5:25am April 13th 2017 via Hootsuite
Whitchurch: Investing in vertical flow, paper-based Dx, also nanoplasmonics M. #MDxEU17
Whitchurch: "We have Marines that are expert at breaking things". Shows a second, PCR-based one. Lower tier - paper-based device #MDxEU17
5:20am April 13th 2017 via Hootsuite
Whitchurch: In second phase: MesaTech, PCR-based, 30min sample-to-answer, cheap cartridges, reader 'a few $100' #MDxEU17
5:19am April 13th 2017 via Hootsuite
Whitchurch: Types to target: Severe acute systemic febrile illness (SASFI), long list Viral hemorrhagic fevors (VHF), Anthrax etc #MDxEU17
Whitchurch: Then clinical eval of technologies. Shows chart of where their technology may be evaluated #MDxEU17
5:18am April 13th 2017 via Hootsuite
Whitchurch: 'Field-forward Dx': open-source data, biosurveillance. 3 phase approach: eval analytics, assay dev for their needs... #MDxEU17
5:16am April 13th 2017 via Hootsuite
Whitchurch: Also equipment -free. Theirs: PARAMEDIC Predictive, actionable, robus, apadive, mobile, ease of use #MDxEU17
5:15am April 13th 2017 via Hootsuite
Whitchurch: Countermeasures, therapeutics. ASSURED parameters (WHO) affordable, sensitive, specific, user-friendly, rapid #MDxEU17
5:14am April 13th 2017 via Hootsuite
Whitchurch: Prepared for 'just about anything'. Strike a balance between what the military demands, but also regulatory hurdles #MDxEU17
5:13am April 13th 2017 via Hootsuite
Whitchurch: He's in the chem/bio threat area: nerve agents, biothreats, anything that can impede the military from doing their job #MDxEU17
5:12am April 13th 2017 via Hootsuite
Christian Whitchurch (DTRA US) Striking a balance: dev multiplexed POC assays for military and civilian use #MDxEU17
5:11am April 13th 2017 via Hootsuite
Barbulovic-Nad: DMF is a platform technology; Kapplex acquired by Miroculus. https://t.co/nQPNzGNPPt #MDxEU17
5:09am April 13th 2017 via Hootsuite
Barbulovic-Nad: Shows photos of several devices for handheld devices. #MDxEU17
5:06am April 13th 2017 via Hootsuite
Barbulovic-Nad: #MDxEU17 Their company is going a step further - printed electrodes, $0.63/device https://t.co/PoowYtUJIg
5:05am April 13th 2017 via Hootsuite
Barbulovic-Nad: #MDxEU17 Mentions ONT's method (complex term, not captured) and manufacturability '12 https://t.co/cs8kDdRAUC
5:04am April 13th 2017 via Hootsuite
Barbulovic-Nad: #MDxEU17 Able to do electro-chemiluminescence. '14 ref https://t.co/LMtXpUtrOz
5:02am April 13th 2017 via Hootsuite
Barbulovic-Nad: Able to do optical measurements on DMF device '15 ref https://t.co/6EXi64POs2 #MDxEU17
5:01am April 13th 2017 via Hootsuite
Barbulovic-Nad: Magnetic separation. Shows nucleic acid amplification, detection on DMF https://t.co/nzFBQ67omW #MDxEU17
4:58am April 13th 2017 via Hootsuite
Barbulovic-Nad: #MDxEU17 Extraction from FN biopsy '15 ref https://t.co/cdQvthzKVs
4:51am April 13th 2017 via Hootsuite
Barbulovic-Nad: Able to electronically control extraction, from liquid/liquid '09 ref https://t.co/YwHSRr1Ffo #MDxEU17
4:50am April 13th 2017 via Hootsuite
