Ferrara: Will payers value an informatics solution, or just view it as the cost of business? #Tricon
11:52am February 22nd 2017 via Hootsuite
Ferrara: Can the clin and econ evidence the value of informatics in oncology care? Value of ID new care options? Outcomes? #Tricon
Ferrara: Clin NGS may be losing money at the lab level, but at the system level adds a lot of value. #Tricon
11:51am February 22nd 2017 via Hootsuite
Ferrara: Emphasis on broader evidence-based economic impact, practice level impace, clinical outcomes. #Tricon
Ferrara: And financial risk has shifted to providers as well. Pay for perf, quality, pt demographics. Shared savings, paid bundles #Tricon
11:50am February 22nd 2017 via Hootsuite
Ferrara: Integrated delivery networks (IDNs); 70% of oncologists are in IDNs in '10. Vast amt of spending at IDN #Tricon
11:49am February 22nd 2017 via Hootsuite
Ferrara: Pace of innovation in Dx and Rx; molecular testing, targeted Rx = info overload for physicians #Tricon
11:48am February 22nd 2017 via Hootsuite
Ferrara: Information intensive part supports Rx selection, outcomes. Technology / service providers, and detailed activities #Tricon
Ferrara: Key driver is targeted Rx for cancer care; more tests. Targeted in '13 is now 46% of cancer care. 5y OS for CML now 89% #Tricon
11:46am February 22nd 2017 via Hootsuite
Ferrara: Oncology is a top cost concern for payers. '10 cancer was $125B in direct medical costs; $173B by '20 #Tricon
11:45am February 22nd 2017 via Hootsuite
Joe Ferrara (Pres, Boston Healthcare) Value capture in Oncology Informatics #Tricon
11:44am February 22nd 2017 via Hootsuite
Rubin: Additional dimensions are cost, CLIA waivers, compatibility of materials, enabling technology vs productivity increase #Tricon
11:43am February 22nd 2017 via Hootsuite
Rubin: Shows three dimensions - technology challenges, device complexity, and regulatory as three to optimize time-to-market #Tricon
11:42am February 22nd 2017 via Hootsuite
Rubin: Add to list: Multi-color fluorescence and alignment of optics; single-cell technology; POC and UIX; connectivity, portability #Tricon
11:39am February 22nd 2017 via Hootsuite
Rubin: Laundry list of dev challenges - sample prep, disposables, miniturization, detection of MEMS, optics; imaging, throughput #Tricon
11:38am February 22nd 2017 via Hootsuite
Rubin: Customers may have a biomarker and need an instrument; or sample prep for NGS; or dPCR, CTCs. Antibiotic suscept #Tricon
11:34am February 22nd 2017 via Hootsuite
Dick Rubin (VP Accel Biotech) is a contract mfr of analytical tools for life sciences; from dPCR to CTCs to CE to chromatography #Tricon
11:33am February 22nd 2017 via Hootsuite
Ianelli: Points to Kayak (flight search) as an example of how platform works - based upon tissue, type of specimen, sliders etc #Tricon
11:31am February 22nd 2017 via Hootsuite
Mueller: But to derive value, they need to be accessed. Since '12: EMR, cloud compute, and marketplaces (AMZN, eBay) #Tricon
11:29am February 22nd 2017 via Hootsuite
Ianelli: In '09, Biobanking had a lot of hype, 'Number 8 on a list of 10 ideas changing the world' #Tricon
11:28am February 22nd 2017 via Hootsuite
Ianelli: Pulls info from Path and Clin labs, repositories and clin research; and interfaces with industry and academia #Tricon
11:26am February 22nd 2017 via Hootsuite
Christopher Ianelli (CEO iSpecimen MA) a biospecimen marketplace paltform for boht healthcare providers and lifescience researchers #Tricon
11:25am February 22nd 2017 via Hootsuite
Mueller: https://t.co/1fR2wslDqA is their website for more info #Tricon
11:24am February 22nd 2017 via Hootsuite
Mueller: Gives a use case of @iontorrent workflow, integrating Torrent APIs and BioBuilds w/open source tools for mapping, calling #Tricon
Mueller: Security requirements, limited IT and bioinf. resources are limited. #Tricon
11:19am February 22nd 2017 via Hootsuite
Mueller: New methods, workflows of a mix of tech and vendors, software a mixture, reference data from many palces, PHI and HIPAA #Tricon
Mueller: Gives example of data intensive science: from specimen receipt to sample prep, seq, mapping, analysis, reporting #Tricon
11:18am February 22nd 2017 via Hootsuite
Chris Mueller (Founder Lab7 TX) Working on integrating data intensive applications into the clinic #Tricon
11:17am February 22nd 2017 via Hootsuite
Applications in future: Immunotherapy and applying Microbiome #Tricon
11:16am February 22nd 2017 via Hootsuite
Moderator's headlines: HTP screening, genomic sequencing; biobanking has had its struggles. Tech in future? CRISPR, Cloud compute #Tricon
11:15am February 22nd 2017 via Hootsuite
Panel is called 'Emerging technologies and industry perspective',, panelists have 7 min to present at #Tricon about problems, tech & sol
11:11am February 22nd 2017 via Hootsuite
#Tricon - poster winner described fast 30min POC antibiotic resistance detection method.
11:09am February 22nd 2017 via Hootsuite
Diagnostics World (publ of BioIT World) have five finalists for 'Early Innovators' 2, 98, 17; winner is Travis Schlappi of CalTech #Tricon
11:08am February 22nd 2017 via Hootsuite
Great to meet @DCGenomics IRL here at #Tricon!
11:03am February 22nd 2017 via Hootsuite
#Tricon Panel of Leaders from Lab7, iSpecimen, Accell Biotech, Boston Healthcare, BioCartis, SeraCare, NanoString, Silicon Biosystems
RT @pickover: This is a joke that could appeal to mathematicians. https://t.co/EDX9vc5kQL
9:40pm February 21st 2017 via Hootsuite
Garlick: Software available for tracking metrics, and easily report out metrics #Tricon
7:11pm February 21st 2017 via Hootsuite
Garlick: Showes results from @archerdxinc assay, as well as @ThermoFisher Oncomine detection (all except for one not assayed) #Tricon
7:09pm February 21st 2017 via Hootsuite
Garlick: Shows results with @QIAGEN RNAscan assay; all are detected. #Tricon
7:08pm February 21st 2017 via Hootsuite
Garlick: Shows dCPR results across partners: NTRK1/3, ROS1, RET, ALK etc. Done for each lot; 'think about 2y from now' testing again #Tricon
7:07pm February 21st 2017 via Hootsuite
Garlick: 10um FFPE curls or purified version. Each curl obains at least 100ng, typically 200 or 300ng #Tricon
7:06pm February 21st 2017 via Hootsuite
Garlick: Every fusion transcript is digital PCR quantitated, 400bp on each side of the breakpoint. Mfg under 13485 #Tricon
7:05pm February 21st 2017 via Hootsuite
Garlick: 15 Fusion RNAs, @SeraCare announced today a second version @httpseracare https://t.co/Za55wTsGh7 #Tricon
7:04pm February 21st 2017 via Hootsuite
Garlick: Clinical labs need reference samples; you need as much info as possible for highly multiplexed test in 1 run. #Tricon
7:02pm February 21st 2017 via Hootsuite
Garlick: Unique challenges, NGS is much more complex than cyto; Fusion RNAs more complex than most DNA muts; RT also source of var #Tricon
7:01pm February 21st 2017 via Hootsuite
Garlick: There are many QC checkpoints - he counts 12. Requires 'Truth Set', and a continuous monitoring of performance w/software #Tricon
7:00pm February 21st 2017 via Hootsuite
Garlick: NGS can detect unknown fusion pairs, superior to classical FISH. Hernandes showed difficulty on preanalytic, bioinf steps #Tricon
6:59pm February 21st 2017 via Hootsuite
Garlick: Tropomyosine receptor kinase is a Rx target - known as OncD, NTRK1/2/3 now known, leads to oncogenesis #Tricon
6:58pm February 21st 2017 via Hootsuite
Garlick: Darah Aisner from Univ CO with scant amt of sample, kept looking at the data, and EGFR mutation was underlying below cutoff #Tricon
6:57pm February 21st 2017 via Hootsuite
Garlick: SeraCare has used over 50K liters of plasma in the past year for different IVD manufacturers #Tricon
6:56pm February 21st 2017 via Hootsuite
