RT @NIAAAnews: Dr. Koob talks about efforts to reduce college drinking with @NPR http://t.co/JH7nFlNqiB http://t.co/PL8JmfeGWC
6:08pm March 19th 2015 via Twitter Web Client
RT @michaelhoffman: CM: assay DNA mutation, 5hmC, 5mC, RNA, RNA 5mC, proteomics, antibody, chromatin state, others on twins before/during/a…
5:19pm March 19th 2015 via Twitter Web Client
RT @michaelhoffman: CM on Twins study. Scott Kelly on ISS for one year. Mark Kelly monozygotic twin on earth.
RT @michaelhoffman: CM playing with @nanopore MinION. Getting up to 71 kbp reads. Will send one into the space station. Only sequencer you …
RT @michaelhoffman: CM quoted in @Gothamist article entitled "'Licking Subway Poles "Probably Fine,' Says Expert" http://t.co/OgpGjSZre4
4:52pm March 19th 2015 via Twitter Web Client
RT @michaelhoffman: CM: PathoMAP available on http://t.co/66sEE64BT9 See which subway stations are have kimchi- or pizza-associated bacteri…
RT @michaelhoffman: CM: 36% of small molecules in your blood are from the microbiome.
4:42pm March 19th 2015 via Twitter Web Client
RT @michaelhoffman: CM introduces the "epiproteome" to mean post-translational modifications. (Used 2x in PubMed)
RT @michaelhoffman: CM: There are many RNA modifications, including m6A. Enriched at 3' ends of genes. http://t.co/uGfxgpK8Wb
RT @michaelhoffman: CM: single-cell RNA-seq reveals extraordinary heterogeneity. Fluidigm C1, $50/cell.
4:41pm March 19th 2015 via Twitter Web Client
RT @michaelhoffman: CM: Global epigenetic change of tumor can e larger w/in one patient in 6 months than between strangers.
RT @michaelhoffman: CM: You can use epialleles as a barcode to reveal clonality http://t.co/IJK1sV3Nl6 https://t.co/Amz4WEI2q1
4:40pm March 19th 2015 via Twitter Web Client
RT @michaelhoffman: CM: Polymorphic epiallele detection can be highly variable. "Epipolymorphism" http://t.co/2eOUpyKbt1
RT @michaelhoffman: CM: Epigenetic age ("methyl-age") accelerated in most cancers. Mean is 36 years.
RT @michaelhoffman: .@mason_lab at Princess Margaret Cancer Centre: "Genome profiling for single cells, entire cities, and the internationa…
.@notSoJunkDNA @michaelhoffman @mason_lab I've done it before - not an easy task!
4:39pm March 19th 2015 via Twitter Web Client in reply to notSoJunkDNA
RT @NIAAAnews: "Cortisol Dysregulation and Alcoholism: Consequence, Correlation or Causality," Dr. Gary Wand @1:30, videocast link: http://…
1:41pm March 19th 2015 via Twitter Web Client
RT @fluidigm: We make microfluidic and mass cytometry systems for #singlecell RNA, DNA, and protein. Our events aren't bad either. http://t…
7:54pm March 18th 2015 via Twitter Web Client
RT @JasonWilliamsNY: Never seen a protein gel in cookbook before. 'Mastering Pasta' by @marcvetri - maybe he'll come to the lab and cook ht…
6:54am March 18th 2015 via Twitter Web Client
RT @matthewherper: The real reason medical residents make just $47,000 a year, study suggests http://t.co/tRc2K6mX2c featuring 30-under-30e…
6:06pm March 17th 2015 via Twitter Web Client
This mind blowing new 3D printing technique is inspired by Terminator 2 http://t.co/dFeNBLHlkb
10:20pm March 16th 2015 via Twitter Web Client
RT @molcasestud: Now accepting submissions! http://t.co/TPVi3dGlom Clinical case reports in genomics, proteomics, metabolomics #OA #precisi…
3:33pm March 16th 2015 via Twitter Web Client
RT @alanburdick: In case you missed it, Siberia has holes. @ElizKolbert explains why: "The Meaning of Siberia’s Mystery Craters" http://t.…
11:43am March 16th 2015 via Twitter Web Client
RT @carlzimmer: Here we go... @Independent reports Harvard scientists have tested CRISPR on human eggs to rewrite a cancer mutation http://…
12:58pm March 14th 2015 via Twitter Web Client
RT @pickover: #PiDay Pi Day: "What did the palindrome & math lover say when she was offered cake?" Answer: "I prefer pi." http://t.co/bJ
12:56pm March 14th 2015 via Twitter Web Client
RT @EricTopol: "The world needs laboratory rats, and the affluent will do as well as anyone" @TheEconomist #ResearchKit http://t.co/fHH3AFH…
12:45pm March 12th 2015 via Twitter Web Client
RT @BiophysicalSoc: A professor banned laptops, permitting only paper-and-pen note taking. One year later, he presents the results: http://…
10:23am March 12th 2015 via Twitter Web Client
RT @TorontoGenomics: Non-coding DNA is clinically relevant! Targeting Super Enhancers for Rheumatoid Arthritis Treatments http://t.co/fJtI6…
2:39pm March 11th 2015 via Twitter Web Client
CK: Ext visible traits - hair and eye color, Kayser's ref: http://t.co/STydfPzOiO #HIDS15
7:57am March 11th 2015 via Twitter Web Client
CK:With AmpFlSTR Y-Filer - 17 Y-STRs amplified, founder effect (1 shared haplotype among 29 males) #HIDS15
CK: Showed different cases of borther/sister, another of a family. Showed GlobalFiler use for kinship, exclusion work #HIDS15
CK:Able to construct tree. Recently reported here: http://t.co/KxKGPDrR6z #HIDS15
CK:Children male (ages 4 and 5); 1 female mother of 2 adults, other female mother of children, all maternal lineage same #HIDS15
CK: Found graves near 'shamanic tree' close to site, early 18th century. Child outside coffin. Had 2 children, 2 female, 1 male #HIDS15
CK: SNP typing used Snapshot or Agenia MassArray technology, also @appliedbio 3500 and 7500 #HIDS15
CK: Map of Yakutsk, two other areas. Bone (aDNA), teeth & hair too. Autosomal - kinships, Y-STRs for paternity, mt DNA for maternal #HID
CK: 150 graves, 145 remains, 130 of which DNA data ( mt DNA, Y-STRs, autosomal) as they were frozen in tundra. #HIDS15
CK: The Yakuts - an enigmatic ethnic group. Turkic-speaking, cattle-horse breeders, migrated in the 15th-19th century #HIDS15
7:56am March 11th 2015 via Twitter Web Client
Christine Keyser Institute of Legal Medicine, Strasbourg University, France: Discovery of 130 burials in Western Siberia #HIDS15
LR: It gives you the frequency 'what you want', acknowledges @lifetech support. #HIDS15
LR: Illustrates new features of YHRD database, likelihood ratio of paternity, other features. Showed progress from '00 to '14 #HIDS15
LR: YHRD - http://t.co/0SrDVWubYr running for 15y, showed geo distribution. Almost 100K Yfiler entries. Chart of Feb '15 Rel 49 #HIDS15
LR: Another paper illustrating stability of Y-chr 08 Fechner ref http://t.co/xkaMChF1E5 #HIDS15
LR: Showed population structure:Purps et al 2014 Nature Gen http://t.co/AmyEcvflxM from 23 loci #HIDS15
LR: Fast and slowly mutating Y-STRS: u=10^-9 to 10^-12, cp to u=10^-3, mutations start. Shows 1998 ref http://t.co/2AzxNTJLkZ #HIDS15
LR:Accused male w/ 6 brothers: differentiated by 45 markers, only 2 muts of 45 to discriminate 3 of the 6 first-deg relatives #HIDS15
LR: Of 66 cases sperm negative: 59% of these have single Y-STR profile. "Why Jack's point is important." #HIDS15
LR: Showed data for exoneration of a wrongly accused individual. Second full Y-STR match. 3rd: negative for sperm #HIDS15
7:55am March 11th 2015 via Twitter Web Client
LR: 95% of all profiles w/no match to YHRD. 21.6% cases w/o male DNA profile #HIDS15
LR: Study of types of evidence (retrospective), of 287 cases / 2077 stains, 2.8% no profile. 40% cases full single-source Y-STR #HIDS15
