RT @HopkinsMedicine: .@NIHDirector: We are 25% below where we were 10 years ago in #cancer funding. We've got to figure out how to turn it …
9:32pm April 1st 2015 via Twitter Web Client
"The backbone of what we do is chemotherapy"; we're better in targeting. Over 2/3'rds with cancer will live >5y, many longer #CancerFilm
9:31pm April 1st 2015 via Twitter Web Client
With so few targeted therapies, cancer care has remained 'much the same for the past 20y' #CancerFilm
9:30pm April 1st 2015 via Twitter Web Client
Collins: "We need to figure out how to turn that around." The difficult calculation: what to pay for how many months of life?!? #CancerFilm
9:29pm April 1st 2015 via Twitter Web Client
"We need more efficient basic research" "And yet funding for the most basic has not been so tight since 1971" #CancerFilm
Most acute problem in the US, where they set the prices. Other countries - people forgo it. Developing world - not available #CancerFilm
9:28pm April 1st 2015 via Twitter Web Client
"Getting cancer is one of the worst financial things that can happen to you in the United States" #CancerFilm
9:27pm April 1st 2015 via Twitter Web Client
RT @DrMiguelPerales: Cancer costs rising faster than overall healthcare costs #CancerFilm http://t.co/wuiRDgfRgz
9:26pm April 1st 2015 via Twitter Web Client
'$700/mo co-pay is rent', just to keep you alive. #CancerFilm
9:25pm April 1st 2015 via Twitter Web Client
Impact of high cost of cancer care: 'Normal jobs w/awesome insurance, but still major bills, month after month.' #CancerFilm
Due to huge costs, the therapies are hugely expensive. From $5K/y at start. In '12: $100K+/year #CancerFilm
9:24pm April 1st 2015 via Twitter Web Client
Last decade - only 4 targeted therapies per year. And each - only extending for a few months. :( #CancerFilm
9:23pm April 1st 2015 via Twitter Web Client
"Each cancer is a moving target." Klausner NCI. Mr. Gomez - only 6mos LDK stopped working. Tried second med., passed away. #CancerFilm
The problem: resistance. "Cancer cells are constantly mutating, evolving over time." "It transforms the idea of treatment" #CancerFilm
9:21pm April 1st 2015 via Twitter Web Client
Seeing now one of the first lung ca patients who tried LDK. 'Miraculous for some of our patients' Blotches disappear #CancerFilm
9:20pm April 1st 2015 via Twitter Web Client
RT @Aiims1742: #CancerFilm Timeline of the human #genome project #endcancer April 25th = DNA Day (Completion date for HGP) http://t.co/RKU…
9:19pm April 1st 2015 via Twitter Web Client
Medicinal chemists have to make sure it fits the pocket perfectly, but bind to nothing else. '99.9% what you do fails' #CancerFilm
9:18pm April 1st 2015 via Twitter Web Client
The landscape seen more clearly; but 'intimidating chaos'. Focus on ALK: after 7y, ID'd one compound LDK blocking growth signals #CancerFilm
9:17pm April 1st 2015 via Twitter Web Client
"The cancer genome is exceedingly complex" (DePinto, MDAnderson) "It's clear we're dealing with the tip of the iceberg" #CancerFilm
9:15pm April 1st 2015 via Twitter Web Client
Vogelstein: "In many cases the brakes are just gone from the cell" (tumor suppressor genes) along with oncogenes (drivers) #CancerFilm
RT @theNCI: More information about the Cancer Genome Atlas: http://t.co/G9FC2FVQkT #CancerFilm
9:14pm April 1st 2015 via Twitter Web Client
Mukherjee - "Much more complex than just a few genes... in one cancer over 100 genes". #CancerFilm
Collins: "The most exciting was the first meetings, now the fog was blown away, to see the whole landscape" #CancerFilm
9:13pm April 1st 2015 via Twitter Web Client
TCGA - "an incredible team science effort" (Gordon Mills, MD Anderson) #CancerFilm
9:12pm April 1st 2015 via Twitter Web Client
Varmus: "He created what we called a Vogel-gram; you can think of cancer as having a history" #CancerFilm
9:10pm April 1st 2015 via Twitter Web Client
'One has to look through literally billions of bases in the cancer genome'. He ID'd several colon mutations #CancerFilm
9:09pm April 1st 2015 via Twitter Web Client
Tonight starts with Bert Vogelstein at Hopkins - a true hero and creative thinker. #Cancerfilm
9:08pm April 1st 2015 via Twitter Web Client
RT @noahWG: "Sci pubs need to cut out the April Fools' jokes to cultivate the public's trust." Hahahahaha haha ahahahahaha haha!! http://t.…
3:42pm April 1st 2015 via Twitter Web Client
RT @rpalaciosb69: How easy was it to persuade research scientists to get involved in public outreach? http://t.co/DQ6JQSzdtV
10:09am April 1st 2015 via Twitter Web Client
.@RebeccaSkloot Thank you for the follow! Look forward to your tweets.
5:30am April 1st 2015 via Twitter Web Client
Preview of tomorrow night - the ongoing fight. #CancerFilm
10:54pm March 31st 2015 via Twitter Web Client
But 'limited success didn't mean ultimate triumph'. Headline - Avastin fails clinical trial... no could imagine twists & turns. #CancerF
10:53pm March 31st 2015 via Twitter Web Client
'Validates 25y search - the beginning of targeted therapy.' All the information we got - is now being used to help people #CancerFilm
10:51pm March 31st 2015 via Twitter Web Client
'There is a description of herceptin and Gleevec as a four-minute mile.' "You break the idea of the limit." #CancerFilm
10:50pm March 31st 2015 via Twitter Web Client
In '98 - given a green-light for CML, and found a 100% response rate 'unheard of'. Rapid, w/o side effects, amazing to see. #CancerFilm
RT @DrStevenLin: "Retroviruses and the #Genetic Origins of #Cancer, 1970-1993" Dr. Varmus http://t.co/ZLaoVlCt64 #CancerFilm http://t.co/5j…
10:48pm March 31st 2015 via Twitter Web Client
Barbara - 'it's an element of fear... a monkey on your back... that never goes away' #CancerFilm
10:47pm March 31st 2015 via Twitter Web Client
'If the data keeps coming back, this is the way to go, you have to believe it'. Barbara "And it's never come back." #CancerFilm
10:46pm March 31st 2015 via Twitter Web Client
'97 trial complete - 'I ran to Art's office and drew the survival curve.' Herceptin - ave 50% increase in lifespan #CancerFilm
'Activism reached a boiling point' - demanding access; 'it just didn't happen w/cancer before'. 1995 - co agreed to lottery #CancerFilm
10:45pm March 31st 2015 via Twitter Web Client
Yet caution is warranted - so many false hopes. Marty Nelson's death in 1994, activists hold funeral at Genentech's campus #CancerFilm
10:44pm March 31st 2015 via Twitter Web Client
RT @jennifermirsky: Navigating treatment options on a patient's own terms. "If I'm going to die, I don't want to die bald and throwing up."…
10:42pm March 31st 2015 via Twitter Web Client
Barbara Bradfield herself - first patient of herceptin (Genentech), news hailed as a 'breakthrough'. #CancerFilm
RT @TeakyW: Watching #CancerFilm and thinking of all the folks in my life touched by cancer. Great book, moving documentary.
10:36pm March 31st 2015 via Twitter Web Client
John Bailar "More are dying of cancer than the year before; how does this match up w/reports of wonderful progress?" #CancerFilm
10:07pm March 31st 2015 via Twitter Web Client
"There was deep chasm between the lab and the clinic that no one could bridge" 1986: "Progress against cancer?" #CancerFilm
10:06pm March 31st 2015 via Twitter Web Client
Wilson: "Being an oncologist, this is who I am." 'You know how the story will end.' #CancerFilm
10:05pm March 31st 2015 via Twitter Web Client
Hard to see Dr. Lori Wilson, w/double mastectomy. Risk coming back is 50%. (Hearing their stories in their own words is hard.) #CancerFilm
10:04pm March 31st 2015 via Twitter Web Client
'We have not slain our enemy, the cancer cell. We have only seen our monster more clearly.' Varmus #CancerFilm
10:01pm March 31st 2015 via Twitter Web Client
The first oncogene, ras, was discovered by Weinberg. 'First time there was a mechanistic explanation. A total revolution.' #CancerFilm
10:00pm March 31st 2015 via Twitter Web Client
