Q: Expect children to become scientists? #BHCRForum18 Two panelists (6 adult children between them) none; another h… https://t.co/eCilXfpuZ0
11:29am April 24th 2018 via Twitter Web Client
Q:To what level do you interact w/public? #BHCRForum18 Solomon: A really impt thing GeneDx mgmt does.
11:28am April 24th 2018 via Twitter Web Client
Q: What's next? Satisfied if this is as far as you go? #BHCRForum18 Kulkarni: yes. Jackson: Feels there's more. Sol… https://t.co/bJB6WLtglK
11:21am April 24th 2018 via Twitter Web Client
Q:What's the first thing you do in the AM? #BHCRForum18 Solomon: instead of PubMed now over LinkedIn and Twitter. Also automated tools.
11:19am April 24th 2018 via Twitter Web Client
Q: % outward-facing? Kulkarni: about 60% #BHCRForum18 Solomon: fluctuates. CSO's role is often 'a sanity check' for new ideas.
11:13am April 24th 2018 via Twitter Web Client
Kulkarni: #BHCRForum18 When you try something new, you will often fail. You will be the positive energy around inno… https://t.co/sa2Ss80dpD
11:10am April 24th 2018 via Twitter Web Client
Danos: #BHCRForum18 Everything from ID to IND; can be done w/a variety of partners, experts.
11:09am April 24th 2018 via Twitter Web Client
Q: What does a CSO do? #BHCRForum18 Solomon: When you get to a certain size, you need a way to track and be acct'ble
11:02am April 24th 2018 via Twitter Web Client
CSOs #BHCRForum18 Solomon: single-best thing was to hire a top CSO, didn't have a traditional one before 'made a world of difference'
11:00am April 24th 2018 via Twitter Web Client
CSOs #BHCRForum18 Solomon (GeneDx) founded by NIH scientists, spun out to do tests for pts. Started in rare disease… https://t.co/N19xlBmoVk
CSOs #BHCRForum18 Kulkarni (Avantor) now is VWR and JT Baker - 13k empl. $6.5B value closed Nov '17 https://t.co/yCaN8QQAM4
10:57am April 24th 2018 via Twitter Web Client
CSOs #BHCRForum18 Danos (RegenX) gene therapy co, started in Philly now in Rockville. AAV-based, 4 active trials incl wet macular degen
10:55am April 24th 2018 via Twitter Web Client
CSOs #BHCRForum18 Jackson (Emergent) intro: Anthrax from DoD and HHS, local success story. Mid-size pharma, see themselves as gov't partner
10:52am April 24th 2018 via Twitter Web Client
Tales of CSO's #BHCRForum18 Steve Projan (AZ) James Jackson (Emergent) Olivier Danos (RegenXBio) Ashish Kulkarni (A… https://t.co/J6QWdAsnJF
10:50am April 24th 2018 via Twitter Web Client
Salgaller: #BHCRForum18 Tech transfer: not competitive nor deadline for appl. Five types of agreements; address gap… https://t.co/UPcxS3OXju
10:29am April 24th 2018 via Twitter Web Client
Salgaller: #BHCRForum18 They have 60 people in licensing. Cumbersome - no, experts in transactions. Internal ideas only, no...
10:24am April 24th 2018 via Twitter Web Client
Salgaller: #BHCRForum18 'only basic research' but xl/clin assets. Only drugs: no they have devices, Dx, biomarkers,… https://t.co/1etWDyoiH4
Salgaller: #BHCRForum18'NIH as your tech dev and commercialization partner'. He was 20y in industry; lists 5 myths of working w/NIH...
10:23am April 24th 2018 via Twitter Web Client
Powers: #BHCRForum18 Attractive rare disease area; also Model Of Non-Alcoholic Steatohepatitis (NASH); also NSCLC platform
10:21am April 24th 2018 via Twitter Web Client
Powers: #BHCRForum18 And large Takeda collab https://t.co/O6O3SgQi7q (up to $470M)
10:19am April 24th 2018 via Twitter Web Client
James Powers (HemoShear Ther.) #BHCRForum18 and Michael Salgaller (NCI). Collaborates with Childrens Nat'l: Propion… https://t.co/MjBqEivuhk
10:18am April 24th 2018 via Twitter Web Client
The winner of the Crab Trap: Galen Robotics #BHCRForum18 Johns Hopkins - $10K award.
10:13am April 24th 2018 via Twitter Web Client
List of #BHCRForum18 Crab Trap participants https://t.co/PYlUJbvnsn
10:09am April 24th 2018 via Twitter Web Client
RenAlert: #BHCRForum18 Tackling acute kidney injury. 15% of 600K US cardiac surgeries get AKI (perfusion). 2% on dialysis.
9:49am April 24th 2018 via Twitter Web Client
Galen Robotics: #BHCRForum18 Improved dexterity, can put in virtual safety features, can be used for training. Market: $21B, 21% 5y CAGR
9:41am April 24th 2018 via Twitter Web Client
Galen Robotics: #BHCRForum18 Only 'cooperatively controlled robot'. Accomodates standard instruments (endoscope). Shows video.
9:39am April 24th 2018 via Twitter Web Client
Galen Robotics: #BHCRForum18 'rockstar surgeons' are rare, limited supply. Existing robotic systems are unaffordable, unflexible
9:38am April 24th 2018 via Twitter Web Client
Galen Robotics: #BHCRForum18 Making critical surgeries safer. Min invasive surgery has benefits, but long tools to reach a small spot
9:36am April 24th 2018 via Twitter Web Client
Q: Pos. against FMI, others in liquid biopsy? Cellth Systems: #BHCRForum18 GRAIL bets on a win; alt is cancer is to… https://t.co/feft8H6hN7
9:35am April 24th 2018 via Twitter Web Client
Cellth Systems: #BHCRForum18 Involved with 2 CTC co's now. Also working with a large pharma.
9:33am April 24th 2018 via Twitter Web Client
Q: Commercial model? Cellth Systems: #BHCRForum18 Decentralized approach: product + software. Agnostic to users. >40 co's on CTC enrichme
Q: How does this fit into I-O or tumor het? Cellth Systems: #BHCRForum18 Heterogeneity: looks at 1000's, tens of K.… https://t.co/kzBaDomiPn
9:32am April 24th 2018 via Twitter Web Client
Cellth Systems: #BHCRForum18 Seeking $2M to expand dataset, software, and GMP setup.
9:30am April 24th 2018 via Twitter Web Client
Cellth Systems: #BHCRForum18 Shows movie. Chip, use existing microscopy, and software. Shows analysis, drug-test, data
9:29am April 24th 2018 via Twitter Web Client
Cellth Systems: #BHCRForum18 PEM (polyelectrolyte membrane) on slide; lipid tethers on PEMs, immob. Drug flows through channel
9:28am April 24th 2018 via Twitter Web Client
Cellth Systems: #BHCRForum18 Pt-spec result in 1h; no cell-growth req. Growth models: glass or plastic adherence req'd.
9:27am April 24th 2018 via Twitter Web Client
Cellth Systems: #BHCRForum18 $7.8M non-dil funding to-date. Problem: current systems require cell culture. Organoid… https://t.co/P1bwfSTgUO
9:26am April 24th 2018 via Twitter Web Client
Cellth Systems: #BHCRForum18 Primary cell models (PDX), results in 2h vs 6w or 6mo. $1B market prior to FDA. 90% margin, disp device
9:24am April 24th 2018 via Twitter Web Client
Cellth Systems: #BHCRForum18 Pt spec drug selection w/tetherscreen: a pers med device for ideal Rx drug for cancer pts
Q: Addressable market? Final use? Algometrix: #BHCRForum18 Want to be in every clinical pain trial. Hosp reimb. needed, several years out.
9:22am April 24th 2018 via Twitter Web Client
Q: Anything to help avoid misuse/abuse of opioids? Algometrix: #BHCRForum18 Use to help precision dosing, and right… https://t.co/NW9ZQahxZv
9:21am April 24th 2018 via Twitter Web Client
Q: Sales model? Algometrix: #BHCRForum18 Want dist. channel, existing medical device co's. MSL's needed for device/pain.
9:20am April 24th 2018 via Twitter Web Client
Algometrix: #BHCRForum18 Purusing fast-track FDA; expected annual license model. Area collabs including Children's Nat'l, NIH, GWU
9:19am April 24th 2018 via Twitter Web Client
Algometrix: #BHCRForum18 Shows baseline, monitor on finger, shows data of pt on opiods, at different freq. Diff Rx, shows effect
9:16am April 24th 2018 via Twitter Web Client
Algometrix: #BHCRForum18 Pain is subjective; Nociometer determine pain type, intensity. Eyecup device, box. Pupillary light reflex
9:14am April 24th 2018 via Twitter Web Client
Crab Trap judge: Bethany Mancilla (VP Amgen) #BHCRForum18 Aglometrix first-up. Handheld device to measure pain. Opi… https://t.co/UQruqPVA30
9:12am April 24th 2018 via Twitter Web Client
Crab trap judges con't: #BHCRForum18 Paul Silber (Blu Venture Investors), Robert Silverman (Head Partnering Roche),… https://t.co/v6e4lIdLWZ
9:11am April 24th 2018 via Twitter Web Client
Crab Trap: 5 startup forum 7min #BHCRForum18 Shaun Grady (VP AstraZeneca), Sara Nayeem (New Enterprise Assoc), John Rubin (JP Morgan)...
Edwards: #BHCRForum18 Some risk - another org uses data to file regulatory; another org files a 'use' patent.
9:05am April 24th 2018 via Twitter Web Client
Edwards: #BHCRForum18 Chemsitry plans are all in public, monthly presentations, B-I is telling abt their internal (killed) program
9:04am April 24th 2018 via Twitter Web Client
